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Dimethylnitrosamine

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Definition: A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.      Other names Nitrosodimethylamine; Nitrosodimethylamine, NDMA; N Nitrosodimethylamine; NDMA Nitrosodimethylamine; N-Nitrosodimethylamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(N-methyl-N-nitrosamino)methyl benzoate  57629-98-8 Methanol, (methylnitrosoamino)-, (11beta,16alpha)  Dimethylnitrosamine/*analogs & derivatives. Carcinogenesis 1984;5(10):1231
1-(N-methyl-N-nitrosamino)methyl pivaloate  93614-10-9 Propanoic acid, 2,2-dimethyl-, (3alpha,5beta,7alpha,12alpha,24xi)  Dimethylnitrosamine/*analogs & derivatives. Carcinogenesis 1984;5(10):1231
methyl(butyroxymethyl)nitrosamine  67557-56-6   Dimethylnitrosamine/*analogs & derivatives. Biochemistry 1981;20(8):2251
N-methyl-N-nitroso-(4-methylphenyl)methylamine  62783-50-0   Dimethylnitrosamine/*analogs & derivatives. Cancer Lett 1979;8(2):125
N-methyl-N-nitroso-(3-methylphenyl)methylamine  62783-49-7   Dimethylnitrosamine/*analogs & derivatives. Cancer Lett 1979;8(2):125
N-methyl-N-nitroso-(2-methylphenyl)methylamine  62783-48-6   Dimethylnitrosamine/*analogs & derivatives. Cancer Lett 1979;8(2):125
methylethylnitrosamine  10595-95-6   Dimethylnitrosamine/*analogs & derivatives. Cancer Res 1980;40(1):19; JNCI 61(2):517;1978
nitrosobenzylmethylamine  937-40-6 N-methyl-N-nitroso-benzenemethanamine  Dimethylnitrosamine/*analogs & derivatives.
Pharma Action Carcinogens 		Cancer Lett 2(6):305;1977; Cancer Lett 7(2-3):115;1979; Environ N-Nitroso Cpds Anal Form W1 121K No.14:27;1976; Gan 69(4):487;1978; IARC Sci Publ 19:503;1978; J Cancer Res Clin Oncol 1979;95(2):123; JNCI 61(1):145;1978; JNCI 61(6):1471;1978
methyl(acetoxymethyl)nitrosamine  56856-83-8 methanol, (methylnitrosoamino)-, acetate (ester)  Dimethylnitrosamine/*analogs & derivatives.
Pharma Action Carcinogens 		Arch Pathol Lab Med 1980;104(4):187; Biochem Pharmacol 1980;29(3):383; Cancer Res 1979;39(12):5136; Cancer Res 39(5):1462;1979; JNCI 58(5):1531;1977; JNCI 63(1):93;1979; Science 1981;214(4520):558; Vet Pathol 16(5):574;1974; Z Krebsforsch 1979;95(1):39; Z Krebsforsch 92(1):105;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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