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Clodronic Acid
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Definition
: A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.
Pharmacological Action
Bone Density Conservation Agents
Other names
Dichloromethylene Diphosphonate; Clodronate; Sodium, Clodronate; Disodium, Clodronate; Diphosphonate, Dichloromethylene; Biphosphonate, Dichloromethylene; Acid, Dichloromethanediphosphonic; Diphosphonate, Dichloromethane; Acid, Clodronic; Dichloromethylenebisphosphonate; Dichloromethylene Biphosphonate; Dichloromethanediphosphonic Acid; Dichloromethanediphosphonate; Dichloromethane Diphosphonate; Clodronate Sodium; Clodronate Disodium; Cl2MDP; Bonefos
Substance
CAS Registry & name
Categories
Source
Drugs
*
pentoxifylline-
tocopherol-
clodronate
0
*Clodronic Acid
*Pentoxifylline
*Tocopherols
Drug Combinations
Osteoradionecrosis/drug therapy
Bone Density Conservation Agents.
Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3);832-9
difluoromethylenesulfonic acid
0
Clodronic Acid/*analogs & derivatives.
Bioorg Med Chem 2002 Jul;10(7):2309-23
difluoromethylene diphosphonate
10596-32-4
Clodronic Acid/*analogs & derivatives.
Metab Bone Dis Relat Res 1983-84;5(1):13