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Colistin

More information in Books or onNLM PubMed
Definition: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.     
Pharmacological Action Anti-Bacterial Agents 		Other names Polymyxin E; Sulfomethate, Colistin; Sulfate, Colistin; Totazina; Coly-Mycin; Colistin Sulfomethate; Colistin Sulfate; Colisticin; ColimycinDrugs* : COLY-MYCIN S
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
chloramphenicol, colistimethate sodium, rolitetracycline drug combination  0   *Chloramphenicol *Colistin *Rolitetracycline Drug Combinations. Vestn Oftalmol 1998 Mar-Apr;114(2):32-4
Eubetal  0   *Betamethasone *Chloramphenicol *Colistin *Tetracycline Drug Combinations. Rev Int Trach Pathol Ocul Trop Subtrop Sante Publi 1991;68:83-7
colistin nonapeptide  32530-94-2 Polymyxin E1, 1-de(N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-, (S)  *Colistin *Peptide Fragments Peptides, Cyclic. J Antibiot (Tokyo) 1984;37(8):926
colistin heptapeptide  75748-25-3 Polymyxin E1, 1-de(N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-2-de-L-threonine-3-de(L-2,4-diaminobutanoic acid)-, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))  *Colistin *Peptide Fragments Peptides, Cyclic. J Antibiot (Tokyo) 1984;37(8):926
colistimethate  12705-41-8   Colistin/*analogs & derivatives. Antimicrob Ag Chemother 8(1):50;1975; J Am Med Assoc 237(14):1481;1977COLY-MYCIN M; COLISTIMETHATE SODIUM

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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