encyclopedia of medical concepts
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Choline

More information in Books or onNLM PubMed
Definition: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.  /biosyn /physiol permitted   
Pharmacological Action Lipotropic Agents; Nootropic Agents
Examples Platelet Activating Factor 		Other names Vidine; Fagine; Bursine; O-Sulfate, Choline; Citrate, Choline; Choline O Sulfate; Chloride, Choline; Bitartrate, Choline; Choline O-Sulfate; Choline Citrate; Choline Chloride; Choline Bitartrate; 2-Hydroxy-N,N,N-trimethylethanaminium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
choline fibrate  0   *Fenofibrate Choline/*analogs & derivatives. Drugs Today (Barc). 2010 Oct;46(10):757-64TRILIPIX
6-methoxy-N-ethylcholine iodide  0   Choline/*analogs & derivatives Molecular Probes. Dokl Biol Sci. 2010 Jan-Feb;430():45-7
2-methacryloyloxyethyltriethylammonium  0   *Methacrylates Choline/*analogs & derivatives. Biopolymers 2009 Nov;91(11):966-73
1-naphthylurethane choline  0   Choline/*analogs & derivatives. Anal Chim Acta. 2009 Jun 30;644(1-2):90-4
Holisal  0   *Salicylates Cellulose/*analogs & derivatives Choline/*analogs & derivatives Glycerol/*analogs & derivatives. Georgian Med News 2008 Jan;(154):36-9
(2-hydroxyethyl)trimethylammonium aluminate  0   Choline/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2006 Nov;65(3-4):753-8
fluoromethylcholine  0   Choline/*analogs & derivatives Fluorine Radioisotopes. Ann Nucl Med. 2006 Oct;20(8):527-33
fluorocholine  0   Choline/*analogs & derivatives Fluorine Radioisotopes. J Nucl Med. 2006 Feb;47(2):262-9
3-(2-(N,N,N-trimethylammonium)ethoxy)pyridine  0   *Pyridines Choline/*analogs & derivatives. Bioorg Med Chem Lett 2006 Aug 15;16(16):4283-6
N-cyclohexylcholine  0   Choline/*analogs & derivatives. J Drug Target 2005 May;13(4):259-66
benzylthiocholine iodide  0   Choline/*analogs & derivatives. Clin Chim Acta 2005 Jan;351(1-2):65-72
deshydroxyfluorocholine  0   Choline/*analogs & derivatives Fluorine Radioisotopes. Nucl Med Biol 2004 Oct;31(7):851-8
choline methacrylate  0   *Methacrylates Choline/*analogs & derivatives. Biomaterials 2004 Jul;25(15);3099-108
choline analog G25  0   Choline/*analogs & derivatives. Antimicrob Agents Chemother. 2004 Aug;48(8):2816-24
(2-(2,2-dimethylpropionyloxy)ethyl)trimethylammonium  0   Choline/*analogs & derivatives. Neurosci Lett 2004 Feb 19;356(3):199-202
4-((3-trifluoromethyl)-3H-diazirin-3-yl)benzoylcholine  0   *Azirines Choline/*analogs & derivatives Receptors, Nicotinic/antagonists & inhibitors. Biochemistry 2003 Jan 21;42(2):271-83
fluoroethylcholine  0   Choline/*analogs & derivatives Fluorine Radioisotopes. J Nucl Med 2002 Feb;43(2):187-99
methyl carbon-11 choline  0   Choline/*analogs & derivatives. Eur J Nucl Med. 2001 Nov;28(11):1664-70
hexadecyl O-phosphonomethylcholine  0   *Phosphonic Acids Choline/*analogs & derivatives. J Med Chem 2001 Dec 6;44(25):4462-7
2-hydroxyethyltriphenylphosphonium choline  0   *Organophosphorus Compounds Choline. Cancer Lett 1999 Jun 1;140(1-2):189-94
CUDA protein, Staphylococcus xylosus  EC 1.2.1.8   *Bacterial Proteins *Betaine-Aldehyde Dehydrogenase Choline. J Bacteriol 1999 Apr;181(7):2273-8
Biotrol  0   *Choline *Inulin *Picolinic Acids *Vanadium Compounds Dietary Supplements. Adv Ther 1998 Sep-Oct;15(5):305-14
PcpA protein, Streptococcus  0   *Bacterial Proteins *Carrier Proteins Choline. FEMS Microbiol Lett 1998 Jul 1;164(1):207-14
suberyldithiocholine  0   Choline/*analogs & derivatives. Zh Evol Biokhim Fiziol 1997 May-Jun;33(3):308-12
triethylcholine  302-61-4   Choline/*analogs & derivatives.
benzilylcholine mustard  5746-42-9   Choline/*analogs & derivatives.
phosphonium choline  58887-04-0   *Organophosphorus Compounds Choline/*analogs & derivatives. Magn Reson Med 1995 Mar;33(3):285-92
alpha-methylcholine  21618-46-2   Choline/*analogs & derivatives. J Neurochem 1994 Apr;62(4):1449-57
selenonium choline  135001-09-1   *Organoselenium Compounds Choline/*analogs & derivatives. Gen Pharmacol 1992 Jul;23(4):689-92
choline transporter  0   *Membrane Transport Proteins Choline Choline/metabolism. J Biol Chem 1990;265(26):15996
3,3'-dithiopropionyl-1-sulfosuccinimidyl 1'-glycyl-tyrosyl cholamine  119463-04-6   *Dipeptides Choline/*analogs & derivatives. Nature 1990;346(6285):655
azelainylcholine  126281-64-9   Choline/*analogs & derivatives. Comp Biochem Physiol (C) 1989;94(1):285
methoxycarbonylcholine  70384-36-0   Choline/*analogs & derivatives. Acta Crystallogr C 1988;44(Pt 5):841
chlorozil  77214-85-8   Choline/*analogs & derivatives. Gen Pharmacol 1987;18(5):569
metacine  1553-33-9   *Benzilates Choline/*analogs & derivatives. Gen Pharmacol 1987;18(5):569
homopahutoxin  109777-68-6 Ethanaminium, N,N,N-trimethyl-2-((1-oxo-3-(1-oxopropoxy)hexadecyl)oxy)-, chloride, (+)  Choline/*analogs & derivatives Marine Toxins. Toxicon 1987;25(4):459
pahutoxin  27742-14-9   Choline/*analogs & derivatives Marine Toxins. Toxicon 1987;25(4):459
ethylcholine aziridinium  63918-37-6   *Aziridines Choline/*analogs & derivatives Toxins, Biological.
Pharma Action Neuromuscular Blocking Agents 		Pharmacol Biochem Behav 1985;22(2):297
methacyne  95548-36-0   Choline/*analogs & derivatives. Biofizika 1985;30(1):23
beta-methylcholine  7562-87-0   Choline/*analogs & derivatives. Life Sci 1985;36(12):1183
N,N,N-triethylhomocholine  53875-77-7 1-Propanaminium, N,N,N-triethyl-3-hydroxy-, (11beta,16alpha)  Choline/*analogs & derivatives. J Neurochem 1984;43(4):1143
N-ethylhomocholine  123731-09-9 1-Propanaminium, N-ethyl-3-hydroxy-N,N-dimethyl  Choline/*analogs & derivatives. J Neurochem 1984;43(4):1143
N,N-diethylhomocholine  32427-94-4   Choline/*analogs & derivatives. J Neurochem 1984;43(4):1143
bis(choline)-N-(4-nitrobenzo-2-oxa-1,3-diazol-7-yl)imino dipropionate  93775-36-1 5,13-Dioxa-9-aza-2-azoniapentadecan-15-aminium, N,N,N,2,2-pentamethyl-9-(7-nitro-4-benzofurazanyl)-6,12-dioxo-, (3beta,5beta)  Choline/*analogs & derivatives. Mol Pharmacol 1984;26(1):57
O-acetyl-N-amino-N,N-dimethylaminoethanol  85916-80-9 Hydrazinium, 1-(2-(acetyloxy)ethyl)-1,1-dimethyl  Choline/*analogs & derivatives. Anal Biochem 1983;130(1):88
N-amino-N,N-dimethylaminoethanol  44519-37-1 Hydrazinium, 1-(2-hydroxyethyl)-1,1-dimethyl  Choline/*analogs & derivatives. Anal Biochem 1983;130(1):88
pentanoylcholine  16597-24-3   Choline/*analogs & derivatives. J Pharmacobiodyn 1982;5(12):1024
acetylarsenocholine  39895-82-4 Arsonium, (2-(acetyloxy)ethyl)trimethyl  *Arsenicals Choline/*analogs & derivatives. J Neurochem 1982;39(3):871
9-anthroylcholine  74095-55-9 Ethanaminium, 2-((9-anthracenylcarbonyl)oxy)-N,N,N-trimethyl  Choline/*analogs & derivatives. Biochem Biophys Res Commun 1982;106(4):1331
antimony choline  81435-66-7 Stibonium, (2-hydroxyethyl)trimethyl  *Organometallic Compounds Choline/*analogs & derivatives Antimony. Biochem Pharmacol 1981;30(21):3003
palmitoylcholine  13100-90-8   Choline/*analogs & derivatives Fish Venoms. Biochem J 1981;193(2):607
O-(2-hydroxyethyl)choline  41830-55-1 ethanaminium, 2-(2-hydroxyethoxy)-N,N,N-trimethyl-, iodide  Choline/*analogs & derivatives. Toxicol Appl Pharmacol 1980;54(2):265
O-(2-iodoethyl)choline  76584-53-7 Ethanaminium, 2-(2-iodoethoxy)-N,N,N-trimethyl  Choline/*analogs & derivatives. Toxicol Appl Pharmacol 1980;54(2):265
O-(2-bromoethyl)choline  76584-54-8   Choline/*analogs & derivatives. Toxicol Appl Pharmacol 1980;54(2):265
O-(2-chloroethyl)choline  74886-55-8 Ethanaminium, 2-(2-chloroethoxy)-N,N,N-trimethyl  Choline/*analogs & derivatives. Toxicol Appl Pharmacol 1980;54(2):265
O-ethylcholine  4358-14-9   Choline/*analogs & derivatives. Toxicol Appl Pharmacol 1980;54(2):265
1-pyrenebutyrylcholine  57440-79-6   Choline/*analogs & derivatives. Biochemistry 1980;19(15):3414
3-toluoyl choline  28080-46-8 ethanaminium, N,N,N-trimethyl-2-((3-methylbenzoyl)oxy)-, iodide  Choline/*analogs & derivatives. Clin Chim Acta 1980;103(3):349
2-toluoyl choline  28418-91-9 ethanaminium, N,N,N-trimethyl-2-((2-methylbenzoyl)oxy)-, iodide  Choline/*analogs & derivatives. Clin Chim Acta 1980;103(3):349
monoethylcholine  13205-69-1 Ethanaminium, N-ethyl-2-hydroxy-N,N-dimethyl  Choline/*analogs & derivatives. Life Sci 1980;26(11):909
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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