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Capsaicin

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Definition: An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.     
Pharmacological Action Antipruritics; Sensory System Agents 		Other names NGX4010; NGX 4010; 8 Methyl N Vanillyl 6 Nonenamide; Zostrix; Zacin; Vinas Brand of Capsaicin; Thompson Brand of Capsaicin; Smaller Brand of Capsaicin; NGX-4010; Medicis Brand of Capsaicin; Link Brand of Capsaicin; Katrum; Gelcen; Flemming Brand of Capsaicin; Elan Brand of Capsaicin; Centrum Brand of Capsaicin; Carter Horner Brand of Capsaicin; Capzasin; Capsin; CapsidolDrugs* : QUTENZA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-palmitoyl-vanillamide  0   Capsaicin/*analogs & derivatives. Pharmacol Res. 2011 Apr;63(4):294-9
coniferyl 8-methylnonanoate  0   Capsaicin/*analogs & derivatives TRPV Cation Channels/agonists. Phytochemistry 2008 Mar;69(5):1179-84
coniferyl (E)-8-methyl-6-nonenoate  0   Capsaicin/*analogs & derivatives TRPV Cation Channels/agonists. Phytochemistry 2008 Mar;69(5):1179-84
isodihydrocapsiate  0   Capsaicin/*analogs & derivatives. Biochem Biophys Res Commun 2008 Jun 27;371(2):289-93
ALGRX-4975  0   *Capsaicin. IDrugs 2008 Feb;11(2):120-32
alpha-carboxy-4,5-dimethoxy-2-nitrobenzyl capsaicin  0   *Benzyl Compounds Capsaicin/*analogs & derivatives. Chembiochem. 2007 Jan 2;8(1):89-97
nordihydrocapsaicin  0   Capsaicin/*analogs & derivatives. Theor Appl Genet. 2006 Nov;113(8):1481-90
N-(4-hydroxy-3-methoxybenzyl)-7-hydroxy-8-methyl-5-nonenamide  0   Capsaicin/*analogs & derivatives. Biosci Biotechnol Biochem 2006 Aug;70(8):1904-12
dohevanil  0   Capsaicin/*analogs & derivatives Apoptosis. Life Sci 2006 Feb 23;78(13):1515-9
5,5'-dicapsaicin  0   Capsaicin/*analogs & derivatives. J Agric Food Chem. 2004 Feb 25;52(4):972-9
N-(4-O-(2-methoxy,phenoxyethylaminobutyl)-3-methoxybenzyl)nonamide  0   Capsaicin/*analogs & derivatives. J Cardiovasc Pharmacol 2003 Oct;42(4);511-20
omega-hydroxycapsaicin  0   Capsaicin/*analogs & derivatives. J Nat Prod 2003 Aug;66(8):1094-6
6'',7''-dihydro-5',5'''-dicapsaicin  0   Capsaicin/*analogs & derivatives. J Nat Prod 2003 Aug;66(8):1094-6
capsiate  0   Capsaicin/*analogs & derivatives. J Agric Food Chem 2002 Dec 4;50(25):7396-401
N-(3-phenylpropyl)-4-hydroxy-3-methoxyphenylacetamide  0   Capsaicin/*analogs & derivatives. Arch Pharm Res 2002 Feb;25(1):25-7
SDZ 249-665  0   Capsaicin/*analogs & derivatives Urea/*analogs & derivatives TRPV Cation Channels/agonists. Pain 2001 Jan;89(2-3):229-35
arvanil  0   Capsaicin/*analogs & derivatives. Biochem Biophys Res Commun 1999 Aug 19;262(1):275-84
civamide  0   Capsaicin/*analogs & derivatives. J Cardiovasc Pharmacol 1998 Dec;32(6):875-83
stearoyl vanillylamide  0   Capsaicin/*analogs & derivatives. J Nutr 1998 Nov;128(11):1978-83
capsazocaine  0   *Benzoates *Oxazoles Capsaicin/antagonists & inhibitors. Gen Pharmacol 1997 Sep;29(3):387-95
capsinolol  0   Capsaicin/*analogs & derivatives. Br J Pharmacol 1996 Sep;119(1):7-14
DA 5018  0   Capsaicin/*analogs & derivatives. Res Commun Mol Pathol Pharmacol 1996 Jan;91(1):97-108
sodium nonivamide acetate  0   Capsaicin/*analogs & derivatives. Biol Pharm Bull 1995 Dec;18(12):1790
KR 25003  0   Capsaicin/*analogs & derivatives. Acta Crystallogr C 1995 May 15;51( Pt 5):927-9
N-(4-O-glycerol-3-methoxybenzyl)nonivamide  147465-43-8   Capsaicin/*analogs & derivatives Glycerol/*analogs & derivatives. Brain Res Bull 1993;30(5-6):641-8
capsazepine  0   Capsaicin/*analogs & derivatives TRPV Cation Channels. Trends Neurosci 1991;14(7):265
NE 21610  118090-17-8 9-Octadecenamide, N-((4-(2-aminoethoxy)-3-methoxyphenyl)methyl)-, (Z)  Capsaicin/*analogs & derivatives. Eur J Pharmacol 1990;181(3):289
olvanil  58493-49-5 9-Octadecenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-, (Z)  Capsaicin/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Drugs Exp Clin Res 1987;13(5):259
nonivamide  618-92-8   Capsaicin/*analogs & derivatives Nitric Oxide Synthase/antagonists & inhibitors.
Pharma Action Sensory System Agents 		Arzneimittelforsch 1984;34(2):154
methylcapsaicin  17514-11-3   Capsaicin/*analogs & derivatives. Biochem Pharmacol 1981;30(7):735
dihydrocapsaicin  19408-84-5   Capsaicin/*analogs & derivatives. J Pharm Soc Jpn 96(2):137;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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