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Butylated Hydroxytoluene

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Definition: A di-tert-butyl PHENOL with antioxidant properties.  consider IONONES if C13-norisoprenoid or ionanes are discussed; DF: BHT;   
Pharmacological Action Antioxidants
Other names Butylhydroxytoluene; BHT; Hydroxytoluene, Butylated; 4 Methyl 2,6 ditertbutylphenol; 2,6 Di tert butyl p cresol; 2,6 Di t butyl 4 methylphenol; Ionol (BHT); Ionol; Dibunol; 4-Methyl-2,6-ditertbutylphenol; 2,6-Di-tert-butyl-p-cresol; 2,6-Di-t-butyl-4-methylphenol; 2,6-Bis(1,1-dimethylethyl)-4-methylphenol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Irganox 3114  0   Butylated Hydroxytoluene/*analogs & derivatives. Anal Chem. 2010 Jan 1;82(1):98-105
3,5-di-tert-butyl-4-hydroxybenzaldehyde  0   *Benzaldehydes Butylated Hydroxytoluene/*analogs & derivatives. Z Naturforsch (C) 2006 May-Jun;61(5-6):458-60
2,6-di-tert-butyl-4-benzoquinone  0   *Benzoquinones Butylated Hydroxytoluene/*analogs & derivatives. Z Naturforsch (C) 2006 May-Jun;61(5-6):458-60
2-tert-butyl-4-methyl-6-iso-propylphenol  0   Butylated Hydroxytoluene/*analogs & derivatives. Chem Res Toxicol 2002 Aug;15(8):1106-12
BDMP-QM  0   *Indoles *Quinones Butylated Hydroxytoluene/*analogs & derivatives. Chem Biol Interact 1997 Nov 28;107(3):185-200
BHTOH-QM  0   *Indoles *Quinones Butylated Hydroxytoluene/*analogs & derivatives. Chem Biol Interact 1997 Nov 28;107(3):185-200
2,6-bis(hydroxymethyl)-4-tert-butylphenol  2203-14-7   Butylated Hydroxytoluene/*analogs & derivatives. Contact Dermatitis 1994 Sep;31(3):154-6
2-hydroxy-5-tert-butylbenzyl alcohol  6638-87-5   Butylated Hydroxytoluene/*analogs & derivatives. Contact Dermatitis 1994 Sep;31(3):154-6
adgenol  0   *Butylated Hydroxytoluene Tissue Adhesives. Khirurgiia (Mosk) 1993 Sep;(9):54-8
LY 231617  93811-58-6   Butylated Hydroxytoluene/*analogs & derivatives. Stroke 1993 May;24(5):716-23
3,5-di-tert-butyl-4-methoxytoluene  1518-53-2   Butylated Hydroxytoluene/*analogs & derivatives. J Pharmacobiodyn 1992 Jul;15(7):333-8
O-sulfo-MK 447  65687-13-0   Butylated Hydroxytoluene/*analogs & derivatives. Eur J Pharmacol 1991 July 23;200(1):141
Epilyt  132338-73-9   *Quaternary Ammonium Compounds *Butylated Hydroxytoluene *Propylene Glycols *Lactic Acid Drug Combinations. J Am Acad Dermatol 1989;20(6):1135
2-tert-butyl-4-methylphenol  2409-55-4   Butylated Hydroxytoluene/*analogs & derivatives. Carcinogenesis 1988;9(1):101
Irganox 1010  6683-19-8   Butylated Hydroxytoluene/*analogs & derivatives. Chung Hua Yu Fang I Hsueh Tsa Chih 1985;19(2):83
WR 194965  69121-82-0   Butylated Hydroxytoluene/*analogs & derivatives. Ann Trop Med Parasitol 1984;78(6):561
2,6-di-tert-butyl-4-hydroxy-4-methyl-2,5-cyclohexadien-1-one  10396-80-2   Butylated Hydroxytoluene/*analogs & derivatives. Toxicol Appl Pharmacol 1983;69(2):283
2-tert-butyl-4-ethylphenol  96-70-8   Butylated Hydroxytoluene/*analogs & derivatives. Toxicol Appl Pharmacol 1983;69(2):283
3,5-di-tert-butyl-4-hydroxytoluene  950-56-1   Butylated Hydroxytoluene/*analogs & derivatives. Cancer Res 1983;43(4):1680
2,6-di-tert-butyl-4-(2'-thenoyl)phenol  69425-13-4   Butylated Hydroxytoluene/*analogs & derivatives. Agents Actions 1982;12(5-6):674
Santowhite powder  85-60-9   Butylated Hydroxytoluene/*analogs & derivatives. Toxicol Lett 1981;8(1-2):77
4,4'-methylenebis(2,6-di-tert-butylphenol)  118-82-1   Butylated Hydroxytoluene/*analogs & derivatives. Toxicol Lett 1981;8(1-2):77
2,2'-methylenebis(ethyl-6-tert-butylphenol)  88-24-4   Butylated Hydroxytoluene/*analogs & derivatives. Toxicol Lett 1981;8(1-2):77
Irganox 1076  2082-79-3 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid octadecyl ester  Butylated Hydroxytoluene/*analogs & derivatives. Food Cosmet Toxicol 1980;18(1):47
4-hydroxy-3,5-di-tert-butyl alpha-methylbenzylamine  0   Butylated Hydroxytoluene/*analogs & derivatives. Izv Akad Nauk SSSR 5:787;1977
2-aminomethyl-4-t-butyl-6-iodophenol  58456-91-0 2-(aminomethyl)-4-(1,1-dimethylethyl)-6-iodophenol  Butylated Hydroxytoluene/*analogs & derivatives.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Diuretics
Agents Actions 1979;9(3):275; Agents Actions 8(6):629;1978; Drug Metab Dispos 1979;7(5):330; J Clin Pharmacol 18(8-9):414;1978; J Pharmacol 208(1):148;1979; Nature 265(5590):170;1977
3,5-di-t-butyl-4-methylphenyl N-methylcarbamate  1918-11-2 2,6-di-t-butyl-4-methylphenyl-N-methylcarbamate  *Carbamates Butylated Hydroxytoluene/*analogs & derivatives. Pesticides 3:302;1975
2,6-di-tert-butyl-4-hydroxymethylphenol  88-26-6   Butylated Hydroxytoluene/*analogs & derivatives. Arch Environ Health 30(10):507;1975
2,2'-thiobis(4-methyl-6-tert-butylphenol)  90-66-4 Phenol, 2,2'-thiobis(6-(1,1-dimethylethyl)-4-methyl  Butylated Hydroxytoluene/*analogs & derivatives. Vopr Onkol 20(7):47;1974
2,2'-methylenebis(4-methyl-6-tert-butylphenol)  119-47-1   Butylated Hydroxytoluene/*analogs & derivatives Sterol O-Acyltransferase/antagonists & inhibitors.
2,4,6-tri(3,5-di-tert-butyl-4-hydroxybenzyl)phenol  6010-34-0 2,4,6-tris((3,5-bis(1,1-dimethylethyl)- 4-hydroxyphenyl)methyl)phenol  *Butylated Hydroxytoluene. Xenobiotica 2(1):1;1972
MON 0585  34624-81-2 2,6-bis(1,1-dimethylethyl)-4-(1-methyl-1-phenylethyl)phenol  Butylated Hydroxytoluene/*analogs & derivatives. Med Parazitol (Mosk) 42(4):480;1973
BH 3  728-39-2 4-(1-aminoethyl)-2,6-bis(1,1-dimethylethyl)phenol  Butylated Hydroxytoluene/*analogs & derivatives. Kosm Biol Med 7(1):9;1973
Ionox 330  1709-70-2 4,4',4''-((2,4,6-trimethyl-1,3,5-benzenetriyl)tris(methylene))tris (2,6-bis(1,1-dimethylethyl))phenol  Butylated Hydroxytoluene/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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