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Blood-Brain Barrier

More information in Books or onNLM PubMed
Definition: Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.  coord IM with endogenous substance /metab (IM) or exogenous substance /pharmacokin (IM)   
See Also Capillary Permeability
Other names Hemato-Encephalic Barrier; Brain-Blood Barrier; Hemato-Encephalic Barriers; Hemato Encephalic Barrier; Brain-Blood Barriers; Brain Blood Barrier; Blood-Brain Barriers; Barriers, Hemato-Encephalic; Blood Brain Barrier; Barriers, Brain-Blood; Barriers, Blood-Brain; Barrier, Hemato-Encephalic; Barrier, Brain-Blood; Barrier, Blood-Brain
 
SubstanceCAS Registry & nameCategoriesSource
Angiopep-2  0   *Peptides Blood-Brain Barrier. Br J Pharmacol 2008 Sep;155(2):185-97
BBB022A  0   Organic Chemicals Blood-Brain Barrier Phosphodiesterase Inhibitors. J Neuroimmunol 1999 Jun 1;97(1-2):119-28
4-trimethylammoniumantipyrine  52526-36-0   *Quaternary Ammonium Compounds Antipyrine/*analogs & derivatives Blood-Brain Barrier. J Pharmacol Toxicol Methods 1992 Nov;28(3):129-35

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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