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Benzidines

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Definition: Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.     
See Also Carcinogens 		Other names Biphenyldiamines; Bianilines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N,N'-bis(1-naphthyl)-N,N'-diphenyl-1,10-biphenyl-4,4'-diamine  0   *Benzidines Diphenylamine/*analogs & derivatives. Adv Mater 2010 Jul 6;22(25):2764-9
3,3'-dipropoxybenzidine  0   *Benzidines. Acta Crystallogr C 2003 Feb;59(Pt 2):071-3
N'-(glutathion-S-yl)-N-acetylbenzidine S-oxide  0   *Benzidines Glutathione/*analogs & derivatives. Drug Metab Dispos 2001 Apr;29(4 Pt 1):401-6
N'-(3'-monophosphodeoxyguanosin-8-yl)-N-acetylbenzidine  0   *Benzidines Deoxyguanosine/*analogs & derivatives. Carcinogenesis 1998 May;19(5):911-7
benzidine N-glucuronide  85559-86-0   *Benzidines *Glucuronates. Carcinogenesis 1992 Jul;13(7):1235-40
3,3'-difluorobenzidine  448-97-5   *Benzidines. Carcinogenesis 1986;7(7):1239
3,3'-dibromobenzidine  34237-98-4 (1,1'-Biphenyl)-4,4'-diamine, 3,3'-dibromo  *Benzidines. Carcinogenesis 1986;7(7):1239
N-(deoxyguanosin-8-yl)benzidine  82682-91-5   *Benzidines Deoxyguanosine/*analogs & derivatives. Carcinogenesis 1986;7(1):179
N-hydroxy-N'-acetylbenzidine  71609-23-9   *Benzidines. Basic Life Sci 1984;29 Pt A:353
benzidine-4,4'-diimine  6050-16-4   *Benzidines. Carcinogenesis 1984;5(11):1499
3,3'-dimethyl-N-acetylbenzidine  3546-13-2   *Benzidines. Ind Health 1982;20(3):727
3,3'-dimethyl-N,N'-diacetylbenzidine  3546-11-0   *Benzidines. Ind Health 1982;20(3):727
N-acetylbenzidine  3366-61-8   *Benzidines. Cancer Res 1982;42(7):2678
2,2',5,5'-tetrachlorobenzidine  15721-02-5   *Benzidines. IARC Monogr Eval Carcinog Risk Chem Human 1982;27:141
benzidine  92-87-5   *Benzidines. J Toxicol Environ Health 1981;7(2):307
3-methoxybenzidine  3365-87-5   *Benzidines. Steroids 1980;36(4):473
3,3',5,5'-tetramethylbenzidine  54827-17-7 3,3',5,5'-tetramethyl(1,1'-biphenyl)-4,4'-diamine  *Benzidines.
Pharma Action Chromogenic Compounds 		Anal Biochem 98(2):388;1979
N,N,N',N'-tetramethylbenzidine  366-29-0 N,N,N',N'-tetramethyl-(1,1'-biphenyl)-4,4'- diamine  *Benzidines. J Histochem Cytochem 1980;28(2):187; J Lab Clin Med 94(2):266;1979
N-hydroxy-N,N'-diacetylbenzidine  71609-22-8 Acetamide, N-(4'-(acetylamino)(1,1'-biphenyl)-4-yl)-N-hydroxy  *Benzidines. Cancer Res 39(8):3107;1979
dicarboxydine  0 gamma,gamma'-3,3'-benzidine dioxydibutyric acid  *Benzidines. JNCI 62(2):301;1979
diazobenzidine  3019-12-3 (1,1'-Biphenyl)-4,4'-bis(diazonium), dichloride  *Benzidines. J Pharm Sci 65(11):1585;1976
2-tolidine  119-93-7   *Benzidines. Digestion 14(5-6):409;1976; Lancet 1(8011):608;1977; Mutat Res 58(2-3):125;1978
N,N'-diacetylbenzidine  613-35-4   *Benzidines. IARC Monogr Eval Carcinog Risk Chem Man 16:293;1978; J Med 6(1):97;1975; Lab Invest 31(3):239;1974
bis(diazo)benzidine  5957-03-9 4,4'-biphenylbis(diazonium)  *Benzidines. J Assn Off Anal Chem 55(5):959;1976
tetraphenylbenzidine  15546-43-7   *Benzidines. Biophys J 13(5):462;1973

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