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Acrylonitrile

More information in Books or onNLM PubMed
Definition: A highly poisonous compound used widely in the manufacture of plastics, adhesives and synthetic rubber.     
Pharmacological Action Carcinogens 		Other names Vinyl Cyanide; Cyanide, Vinyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,3-bis(4-nitrophenyl)acrylonitrile  0   Acrylonitrile/*analogs & derivatives. Biochem Pharmacol. 2012 Mar 1;83(5):627-32.
YHO-13177  0   Acrylonitrile/*analogs & derivatives. Mol Cancer Ther. 2011 Jul;10(7):1252-63
YHO-13351  0   Acrylonitrile/*analogs & derivatives. Mol Cancer Ther. 2011 Jul;10(7):1252-63
2-(4-fluorophenylsulfonyl)-3-(1-(3-nitrophenylsulfonyl)-1H-pyrrol-2-yl)acrylonitrile  0   *Sulfonamides Acrylonitrile/*analogs & derivatives. J Med Chem 2011 Jul 28;54(14):5229-36
2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile  0   *Indoles Acrylonitrile/*analogs & derivatives. Angew Chem Int Ed Engl 2010 Oct 25;49(44):8228-31
3-hydroxy-2-methylene-3-(4-nitrophenylpropanenitrile)  0   *Benzyl Alcohols Acrylonitrile/*analogs & derivatives. Bioorg Chem 2010 Oct;38(5):190-5
3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile  0   *Stilbenes Acrylonitrile/*analogs & derivatives. Biochem Biophys Res Commun 2010 May 28;396(2):440-4
2-acetyl-3-(6-methoxybenzothiazo)-2-ylaminoacylonitrile  0   *Benzothiazoles Acrylonitrile/*analogs & derivatives. Cancer Lett 2009 May 8;277(1):55-63
2-((3,4,5)-trihydroxy-6-hydroxymethyltetrahydropyran-2-yloxymethyl)acrylonitrile  0   *Hexoses Acrylonitrile/*analogs & derivatives. Phytochemistry 2008 Nov;69(16):2815-9
3-dimethylamino-2-(1H-indol-3-ylcarbonyl)acrylonitrile  0   *Indoles Acrylonitrile/*analogs & derivatives. Acta Crystallogr C 2008 Jul;64(Pt 7):o385-7
2-(benzylaminocarbonyl)-3-(3,4-dihydroxystyryl)acrylonitrile  0   *Styrenes Acrylonitrile/*analogs & derivatives. Mol Cancer Ther 2008 May;7(5):1176-84
3-(benzo(b)thiophen-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile  0   *Thiophenes Acrylonitrile/*analogs & derivatives. Acta Crystallogr C 2007 Dec;63(Pt 12):o743-5
3-(benzo(b)thiophen-2-yl)-2-(3,4,5-trimethoxyphenyl)acrylonitrile  0   *Thiophenes Acrylonitrile/*analogs & derivatives. Acta Crystallogr C 2007 Dec;63(Pt 12):o743-5
2-nitrilquinoline  0   *Quinolines Acrylonitrile/*analogs & derivatives. Biomed Pharmacother 2007 Feb-Apr;61(2-3):186-8
(Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile  0   Acrylonitrile/*analogs & derivatives. Bioorg Med Chem Lett. 2007 Feb 15;17(4):993-7
3-isocyanatoacrylonitrile  0   *Isocyanates Acrylonitrile/*analogs & derivatives. J Mol Model 2006 Jul;12(5):731-7
3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile  0   *Thiophenes Acrylonitrile/*analogs & derivatives. Acta Crystallogr C 2004 Mar;60(Pt 3):o217-8
2-(1H-benzimidazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylonitrile  0   *Thiophenes Acrylonitrile/*analogs & derivatives. J Med Chem 2004 Jun 17;47(13):3438-49
2-(benzenesulfonyl)-3,3-bis(methylsulfanyl)acrylonitrile  0   *Sulfones Acrylonitrile/*analogs & derivatives. J Med Chem 2003 Nov 6;46(23):4834-7
1-benzoyl-1-cyano-2-(4,5-dimethoxy-2-nitrophenyl)ethene  0   *Nitrobenzenes Acrylonitrile/*analogs & derivatives beta-Galactosidase/antagonists & inhibitors. J Protein Chem 2000 Feb;19(2):123-8
1,1-dicyano-2-(4,5-dimethoxy-2-nitrophenyl)ethene  0   *Nitrobenzenes Acrylonitrile/*analogs & derivatives beta-Galactosidase/antagonists & inhibitors Papain/antagonists & inhibitors. J Protein Chem 2000 Feb;19(2):117-22
2-(1H-benzotriazol-1-yl)-3-(4-bromophenyl)acrylonitrile  0   *Triazoles Acrylonitrile/*analogs & derivatives. Eur J Med Chem 2000 May;35(5):535-43
2-(1H-benzotriazol-1-yl)-3-phenylacrylonitrile  0   *Triazoles Acrylonitrile/*analogs & derivatives. Eur J Med Chem 2000 May;35(5):535-43
2-(3-(4-methoxyphenyl)pyrazol-5-yl)-3-(2-pyrrolyl)acrylonitrile  0   *Pyrazoles Acrylonitrile/*analogs & derivatives. Bioorg Med Chem 1999 Jul;7(7):1425-36
2-(3-(3-methoxyphenyl)pyrazol-5-yl)-3-(2-pyrrolyl)acrylonitrile  0   *Pyrazoles Acrylonitrile/*analogs & derivatives. Bioorg Med Chem 1999 Jul;7(7):1425-36
2-(1,1-dicyanopropenyl-2-)-6-dimethylaminonaphthaleney  0   Acrylonitrile/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. Bioorg Med Chem Lett 1998 Jun 16;8(12):1455-60
3-(3-amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)acrylonitrile  0   *Anisoles Acrylonitrile/*analogs & derivatives. J Med Chem 1998 Jul 30;41(16):3022-32
kevloc  0   *Heterocyclic Compounds Acrylonitrile/*analogs & derivatives Dental Bonding. J Prosthet Dent 1998 mar;79(3):270-3
acrylonitrile copper sulfide  0   *Sulfides Acrylonitrile/*analogs & derivatives Copper. J Am Geriatr Soc 1990;38(8):889
Clinagel  37291-07-9   *Starch *Acrylonitrile Varicose Ulcer/drug therapy. Z Hautkr 1987;62(1):41
2,3,3-triphenylacrylonitrile  6304-33-2   Acrylonitrile/*analogs & derivatives. J Steroid Biochem 1984;20(1):137
2-chloroacrylonitrile  920-37-6   Acrylonitrile/*analogs & derivatives. Gig Tr Prof Zabol 1983;(2):52
AN-69  60650-36-4   *Acrylic Resins Acrylonitrile/*analogs & derivatives Membranes, Artificial. Proc Clin Dial Transplant Forum 7:170;1978
acrylonitriledimethylaminoethyl methacrylate copolymer  26777-63-9   *Polymethacrylic Acids Acrylonitrile/*analogs & derivatives. Biomater Med Dev Art Org 4(3-4):263;1976; Trans Am Soc Artif Int Org 22:292;1976
hydracrylonitrile  109-78-4 ethylene cyanohydrin  Acrylonitrile/*analogs & derivatives Ethanol/*analogs & derivatives. Nucleic Acid Res 5(4):1253;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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