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Aconitine

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Definition: A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM plants. It activates voltage-gated SODIUM CHANNELS. It has been used to induce arhythmias in experimental animals and it has antiinflammatory and antineuralgic properties.  ACONITE (see ACONITUM) is also available   
Pharmacological Action Adjuvants, Immunologic 		Other names Acetylbenzoylaconine; Acetylbenzoyl aconine; Acetylbenzoyl-aconine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
noroxoaconitine  0   Aconitine/*analogs & derivatives. Cell Mol Life Sci. 2011 Jan;68(2):289-301
isodelelatine  0   Aconitine/*analogs & derivatives. Yao Xue Xue Bao 2008 Sep;43(9):934-7
tuguaconitine  0   Aconitine/*analogs & derivatives. Arch Pharm Res 2008 Feb;31(2):259-63
18-deoxy-13,14-dihydrolycoctam  0   Aconitine/*analogs & derivatives. Acta Crystallogr C 2006 May;62(Pt 5):o283-5
14-O-acetyl-8-O-methyl-18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoylcammaconine  0   *Quinazolines Aconitine/*analogs & derivatives. J Nat Prod 2006 Mar;69(3):400-2
18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoyllycoctonine  0   *Quinazolines Aconitine/*analogs & derivatives. J Nat Prod 2006 Mar;69(3):400-2
alaglyzin  0   *Glycyrrhizic Acid Aconitine/*analogs & derivatives. Eksp Klin Farmakol 2005 Jul-Aug;68(4):24-7
8-O-azeloyl-14-benzoylaconine  0   Aconitine/*analogs & derivatives. Bioorg Med Chem 2005 Dec 1;13(23):6493-501
neoline  0   Aconitine/*analogs & derivatives Alkaloids. Arch Pharm Res. 2003 Sep;26(9):709-15
lipohypaconitine  0   Aconitine/*analogs & derivatives Alkaloids. Arch Pharm Res. 2003 Sep;26(9):709-15
lipomesaconitine  0   Aconitine/*analogs & derivatives Alkaloids. Arch Pharm Res. 2003 Sep;26(9):709-15
16-O-demethylaconitine  0   Aconitine/*analogs & derivatives. Yao Xue Xue Bao 2002 Oct;37(10):781-3
benzoylhypaconine  0   Aconitine/*analogs & derivatives Alkaloids. Leg Med (Tokyo). 2003 Mar;5 Suppl 1():S101-4
14-anisoylaconine  0   Aconitine/*analogs & derivatives. Leg Med (Tokyo). 2003 Mar;5 Suppl 1():S101-4
N-deacetylranaconitine  0   Aconitine/*analogs & derivatives. J Chromatogr A 2002 Jan 18;943(2):219-25
7-hydroxycossonidine  0   Aconitine/*analogs & derivatives. J Nat Prod 2002 Apr;65(4):513-6
8-O-methylcolumbianine  0   Aconitine/*analogs & derivatives. J Nat Prod 2002 Apr;65(4):513-6
olividine  0   Aconitine/*analogs & derivatives. J Nat Prod 2002 Apr;65(4):513-6
olivimine  0   Aconitine/*analogs & derivatives. J Nat Prod 2002 Apr;65(4):513-6
isotalatizidine  7633-68-3   Aconitine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2000 Dec;48(12):1912-6
ajacine  0   Aconitine/*analogs & derivatives. Brain Res 1999 Sep 25;842(2):332-41
eldeline  0   Aconitine/*analogs & derivatives. Eur J Pharmacol 1999 Mar 26;369(3):279-88
6-benzoyldeltamine  0   Aconitine/*analogs & derivatives. Eur J Pharmacol 1999 Mar 26;369(3):279-88
14-benzoyltalitasamine  0   Aconitine/*analogs & derivatives. Naunyn Schmiedebergs Arch Pharmacol 1998 Jun;357(6):585-92
talitasamine  0   Aconitine/*analogs & derivatives. Naunyn Schmiedebergs Arch Pharmacol 1998 Jun;357(6):585-92
lappaconidine  0   Aconitine/*analogs & derivatives. Brain Res 1997 Sep 19;769(1):36-43
N-desacetylappaconitine  0   Aconitine/*analogs & derivatives. Brain Res 1997 Sep 19;769(1):36-43
heteratisine  3328-84-5 Heteratisan-14-one, 20-ethyl-6,8-dihydroxy-1-methoxy-4-, (1alpha,6beta)  Aconitine/*analogs & derivatives. Neuropharmacology 1997 Aug;36(8):1039-46
1-benzoylnapelline  0   Aconitine Ranunculaceae. Eur J Pharmacol 1997 Sep 24;335(2-3):145-52
napelline  5008-52-6   Aconitine Ranunculaceae. Eur J Pharmacol 1997 Sep 24;335(2-3):145-52
TJN 505  131653-96-8   Aconitine/*analogs & derivatives. Eur J Pharmacol 1996 Dec 30;318(2-3):333-40
6-benzoylheteratisine  99759-48-5   Aconitine/*analogs & derivatives. Brain Res 1996 Oct 28;738(1):154-7
3-deoxy-18-O-desmethyl((methylsuccinimido)benzoyl)aconitine  0   Aconitine/*analogs & derivatives. FEBS Lett 1995 May 22;365(1):79-82
3-deoxy-18-O-desmethyl(2-aminobenzoyl)aconitine  0   Aconitine/*analogs & derivatives. FEBS Lett 1995 May 22;365(1):79-82
lycoctonine  26000-17-9   Aconitine/*analogs & derivatives. FEBS Lett 1995 May 22;365(1):79-82
3,15-diacetylbenzoylaconine  119347-27-2 Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 3,15-diacetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)  Aconitine/*analogs & derivatives Aconitum. Chung Kuo Yao Li Hsueh Pao 1994 Mar;15(2):176-80
14-deacetylnudicauline  119347-24-9   Aconitine/*analogs & derivatives Plant Extracts. Vet Hum Toxicol 1994 Feb;36(1):10-4
benzoylmesaconine  63238-67-5   Aconitine/*analogs & derivatives. Nippon Yakurigaku Zasshi 1993 Dec;102(6):399-404
ranaconitine  1360-76-5   Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Chung Kuo Chung Yao Tsa Chih 1992 Sep;17(9):549-50
yunaconitine  70578-24-4   Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Chung Kuo Chung Yao Tsa Chih 1991;16(1):43
talatisamine  20501-56-8   Aconitine/*analogs & derivatives Aconitum. Chung Kuo Chung Yao Tsa Chih 1991;16(1):43
jesaconitine  16298-90-1   Aconitine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1991;39(2):379
aconosine  38839-95-1 Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-, (1alpha,14alpha,16beta)  Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(6):441
8-acetyldolaconine  132160-38-4 Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-, diacetate (ester), (1alpha,14alpha,16beta)  Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(6):441
dolaconine  82841-75-6 Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-, 14-acetate, (1alpha,14alpha,16beta)  Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(6):441
glabredelphinine  132160-37-3 Aconitane-1,6,7,8,14-pentol, 2,3-didehydro-20-ethyl-16-methoxy-4-methyl-, (1alpha,6beta,14alpha,16beta)  Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(6):438
szechenyine  96562-88-8 Aconitane-3,13,14,15-tetrol, 8-ethoxy-20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 3-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)  Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1989;24(1):71
8-acetyl-14-benzoylchasmanine  4296-54-2 Aconitane-8,14-diol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,6alpha,14alpha,16beta)  Aconitine/*analogs & derivatives. Yao Hsueh Hsueh Pao 1988;23(6):460
13,15-dideoxyaconitine  77757-14-3 Aconitane-3,8,14-triol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,16beta)  Aconitine/*analogs & derivatives. Yao Hsueh Hsueh Pao 1988;23(6):460
hypaconitine  6900-87-4   Aconitine/*analogs & derivatives Ranunculaceae. Jpn J Pharmacol 1988;48(2):290
deoxyaconitine  3175-95-9   Aconitine/*analogs & derivatives Drugs, Chinese Herbal. Chung Yao Tung Pao 1988;13(2):33
N-deacetyllappaconitine  11033-64-0   Aconitine/*analogs & derivatives. Chung Kuo Yao Li Hsueh Pao 1987;8(4):301
methyllycaconitine  21019-30-7   Aconitine/*analogs & derivatives Seeds Toxins, Biological Ranunculaceae.
Pharma Action Insecticides ; Nicotinic Antagonists 		FEBS Lett 1988;226(2):357
bulleyaconitine A  107668-79-1   Aconitine/*analogs & derivatives. Yao Hsueh Hsueh Pao 1986;21(12):886
allapinin  97792-45-5   Aconitine/*analogs & derivatives.
Pharma Action Anti-Arrhythmia Agents ; Bronchodilator Agents 		Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSR 1986;9(2):30
methylgymnaconitine  103956-42-9 Aconitane-8,14-diol, 20-ethyl-1,16-dimethoxy-4-(methoxymethyl)-, 14-(3-(3,4-dimethoxyphenyl)-2-propenoate), (1alpha,14alpha(E),16beta)  Aconitine/*analogs & derivatives. Yao Hsueh Hsueh Pao 1986;21(4):279
gymnaconitine  103956-41-8 Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-(methoxymethyl)-, 14-(3-(3,4-dimethoxyphenyl)-2-propenoate), (1alpha,14alpha(E),16beta)  Aconitine/*analogs & derivatives. Yao Hsueh Hsueh Pao 1986;21(4):279
benzoylaconine  466-24-0   Aconitine/*analogs & derivatives. Chung Yao Tung Pao 1985;10(7):22
aconine  509-20-6   Aconitine/*analogs & derivatives. Chung Yao Tung Pao 1985;10(7):22
dielsin B  87714-31-6   Aconitine/*analogs & derivatives. Chung Kuo Yao Li Hsueh Pao 1983;4(3):166
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