encyclopedia of medical concepts
ψ
palonosetron
under Isoquinolines
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Isoquinolines
Definition
: A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
Substance
CAS Registry & name
Categories
Source
Drugs
*
palonosetron [ 2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one,2-QHBIQO,Aloxi,RS 25233-197,RS 25233-198,RS 25259,RS 25259-197,RS 25259-198,RS-25233-197,RS-25233-198,RS-25259,RS-25259-197,RS-25259-198,palonosetron hydrochloride,palonosetron, (R-(R*,R*))-isomer,palonosetron, (R-(R*,S*))-isomer,palonosetron, (S-(R*,S*))-isomer ]
5-HT(3) receptor antagonist; RN given refers to (S-(R*,R*))-isomer; structure given in first source
135729-61-2
*Isoquinolines
*Quinuclidines
Pharma Action
Serotonin Antagonists
J Med Chem 1993 Sep 3;36(18):2645-57
PALONOSETRON HYDROCHLORIDE
;
ALOXI