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ICI D2788

under Pyrimidines
More information in Books or onNLM PubMed
More on Pyrimidines Definition: A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ICI D2788 [ 4-(N-ethyl-N-phenylamino)-1,2-dimethyl-6-(methylamino)pyrimidinium chloride,ICI-D2788,ZD 7288,ZD-7288,ZD7288,ZENECA ZD7288 ]
  a sinoatrial node modulator; may be of use in treatment of ischaemic heart disease by increasing heart rate without impairing cardiac function
133059-99-1   *Pyrimidines Cyclic Nucleotide-Gated Cation Channels
Pharma Action Cardiotonic Agents; Cardiovascular Agents
J Cardiovasc Pharmacol 1993 Jun;21(6):902-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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