Definition: A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.
Other names V Set Domain Containing T Cell Activation Inhibito; T Cell Costimulatory Molecule B7x; Immune Costimulatory Protein B7 H4; T-Cell Costimulatory Molecule B7x; Immune Costimulatory Protein B7-H4; B7H4 Immune Costimulatory Protein