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Class Ib Phosphatidylinositol 3-Kinase

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Definition: A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the association of a p110gamma catalytic subunit and one of the three regulatory subunits of 84, 87, and 101 kDa in size. This subclass of enzymes is a downstream target of G PROTEIN-COUPLED RECEPTORS.      Other names p87 Subunit, Class Ib Phosphatidylinositol 3 Kinas; p84 Subunit, Class Ib Phosphatidylinositol 3 Kinas; p110gamma Subunit, Class Ib Phosphatidylinositol 3; p101 Subunit, Phosphoinositide 3 Kinase; Subunit, Phosphoinositide-3-Kinase p101; Phosphoinositide-3-Kinase p101 Subunit; Phosphoinositide 3 Kinase, Regulatory Subunit 5; Phosphatidylinositol 3 Kinase, Class Ib; Class Ib Phosphatidylinositol 3 Kinases; Class Ib Phosphatidylinositol 3 Kinase, p87 Subuni; Class Ib Phosphatidylinositol 3 Kinase, p84 Subuni; Class Ib Phosphatidylinositol 3 Kinase, p110gamma ; Class Ib Phosphatidylinositol 3 Kinase, p101 Subun; Class Ib Phosphatidylinositol 3 Kinase; p87 Subunit, Class Ib Phosphatidylinositol 3-Kinas; p84 Subunit, Class Ib Phosphatidylinositol 3-Kinas; p110gamma Subunit, Class Ib Phosphatidylinositol 3; p101 Subunit, Phosphoinositide-3-Kinase; Phosphoinositide-3-Kinase, Regulatory Subunit 5; Phosphoinositide-3-Kinase, Catalytic, gamma Polype
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Pik3cg protein, rat  EC 2.7.1.137   *Class Ib Phosphatidylinositol 3-Kinase.
Pik3cg protein, mouse  EC 2.7.1.153   *Class Ib Phosphatidylinositol 3-Kinase.
PIK3CG protein, human  EC 2.7.1.137   *Class Ib Phosphatidylinositol 3-Kinase.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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