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Islet Amyloid Polypeptide

More information in Books or onNLM PubMed
Definition: A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.     
Pharmacological Action Appetite Depressants 		Other names Polypeptide, Islet Amyloid; Polypeptide, Insulinoma Amyloid; Amyloid Polypeptide, Islet; Amyloid Polypeptide, Insulinoma; Amylin, Pancreatic; Pancreatic Amylin; Islet Amyloid Polypeptide Precursor; Insulinoma Amyloid Polypeptide Precursor; Insulinoma Amyloid Polypeptide; IAPP Protein; IAPP Precursor; Amlintide; Amylin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pramlintide  151126-32-8   *Islet Amyloid Polypeptide.
Pharma Action Hypoglycemic Agents 		Diabetes 1997 Apr;46(4):632-6SYMLIN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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