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Sirtuin 2

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Definition: A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.      Other names Silent Mating Type Information Regulation 2 Homolo
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SIRT2 protein, human  EC 3.5.1.-   *Sirtuin 2. Mol Cell Biol 2003 May;23(9):3173-85
HST2 protein, S cerevisiae  EC 3.5.1.-   *Saccharomyces cerevisiae Proteins *Sirtuin 2. EMBO J 2001 Jan 15;20(1-2):197-209
Sirt2 protein, mouse  EC 3.5.1.-   *Sirtuin 2 Zinc Fingers Leucine Zippers. Genomics 2000 Nov 1;69(3):355-69
HST1 protein, S cerevisiae  EC 3.5.1.-   *Saccharomyces cerevisiae Proteins *Sirtuin 2. Yeast 1996 Jun 15;12(7):631-40
Sirt2 protein, rat  0   *Sirtuin 2. J Biochem (Tokyo) 1995 Jul;118(1):122-8
SIR2 protein, S cerevisiae  EC 3.5.1.-   *Silent Information Regulator Proteins, Saccharomyces cerevisiae *Sirtuin 2. Mol Cell Biol 1994 Jul;14(7):4501-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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