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Acid Ceramidase

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Definition: A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Asah1 protein, rat  EC 3.5.1.23   *Acid Ceramidase.
Asah1 protein, mouse  EC 3.5.1.23   *Acid Ceramidase.
ASAH1 protein, human  EC 3.5.1.23   *Acid Ceramidase Farber Lipogranulomatosis.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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