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Growth Differentiation Factor 1

More information in Books or onNLM PubMed
Definition: A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.      Other names GDF-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Gdf1 protein, rat  0   *Growth Differentiation Factor 1.
Gdf1 protein, mouse  0   *Growth Differentiation Factor 1.
GDF1 protein, human  0   *Growth Differentiation Factor 1.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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