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Fatty Acid Synthetase Complex, Type I

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Definition: Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS.      Other names Fatty Acid Synthase, Mammalian
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FASN protein, human  EC 2.3.1.85   *Fatty Acid Synthetase Complex, Type I.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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