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Cyclic Nucleotide Phosphodiesterases, Type 7

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Definition: A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC AMP. Several isoforms of the enzyme type exist, each with its own tissue localization. The isoforms are encoded by at least two genes and are a product of multiple alternative splicing of their mRNAs.      Other names cAMP Phosphodiesterase 7; Phosphodiesterase 7; cAMP Phosphodiesterase-7; Phosphodiesterase-7; PDE7 Phosphodiesterases; Cyclic Nucleotide Phosphodiesterases, Type 7B; Cyclic Nucleotide Phosphodiesterases, Type 7A; Cyclic Nucleotide Phosphodiesterase PDE7 Family
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-cyclohexyl-N-(3-fluoro-4-(4-methyl-1-piperazinyl)phenyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide  0   *Pyrazoles *Thiophenes Cyclic Nucleotide Phosphodiesterases, Type 7/antagonists & inhibitors. Int Immunopharmacol 2009 Oct;9(11):1347-51
1-cyclohexyl-N-(6-(4-hydroxy-1-piperidinyl)-3-pyridinyl)-3-methyl-1H-thieno(2,3-c)pyrazole-5-carboxamide  0   *Pyrazoles *Thiophenes Cyclic Nucleotide Phosphodiesterases, Type 7/antagonists & inhibitors. Int Immunopharmacol 2009 Jan;9(1):97-102
Pde7b protein, rat  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.
Pde7b protein, mouse  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.
PDE7B protein, human  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.
Pde7a protein, rat  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.
Pde7a protein, mouse  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.
PDE7A protein, human  EC 3.1.4.17   *Cyclic Nucleotide Phosphodiesterases, Type 7.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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