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Protein Phosphatase 2

More information in Books or onNLM PubMed
Definition: A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.      Other names Serine Threonine Protein Phosphatase 2A Catalytic ; Protein Phosphatase 2A; Phosphatase, PPP2CB; Phosphatase, PPP2CA; Serine-Threonine-Protein Phosphatase 2A Catalytic ; Serine Threonine Protein Phosphatase 2A Catalytic ; Protein Phosphatase-2A; Protein Phosphatase 2A, Regulatory Subunit B, gamm; Protein Phosphatase 2A, Regulatory Subunit B, delt; Protein Phosphatase 2A, Regulatory Subunit B, beta; Protein Phosphatase 2A, Regulatory Subunit B, alph; Protein Phosphatase 2A, Regulatory Subunit A, beta; Protein Phosphatase 2A, Regulatory Subunit A , alp; Protein Phosphatase 2A, Catalytic Subunit, beta Is; Protein Phosphatase 2A, Catalytic Subunit, alpha I; Protein Phosphatase 2, Regulatory Subunit B, gamma; Protein Phosphatase 2, Regulatory Subunit B, delta; Protein Phosphatase 2, Regulatory Subunit B, beta ; Protein Phosphatase 2, Regulatory Subunit B, alpha; Protein Phosphatase 2, Regulatory Subunit A, beta
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ppp2r5a preotein, mouse  EC 3.1.3.16   *Protein Phosphatase 2. Endocrinology 2010 Aug;151(8):3624-32
PPTR1 protein, C elegans  0   *Caenorhabditis elegans Proteins Protein Subunits Protein Phosphatase 2. Cell 2009 Mar 6;136(5):939-51
PPP2R2B protein, rat  0   *Carrier Proteins Protein Phosphatase 2. J Biol Chem 2008 Dec 26;283(52):36241-8
PPP2R5E protein, human  0   *Protein Phosphatase 2.
PPP2R5D protein, human  0   *Protein Phosphatase 2.
PPP2R5A protein, human  0   *Protein Phosphatase 2.
PPP2R3C protein, human  0   *Protein Phosphatase 2.
PPP2R3A protein, human  EC 3.1.3.16   *Protein Phosphatase 2.
PPP2R2D protein, human  0   *Protein Phosphatase 2.
Ppp2r1b protein, rat  EC 3.1.3.16   *Protein Phosphatase 2.
PPP2R2C protein, human  0   *Protein Phosphatase 2.
PPP2R1A protein, human  0   *Protein Phosphatase 2.
PPP2CB protein, human  EC 3.1.3.16   *Protein Phosphatase 2.
PPP2CA protein, human  EC 3.1.3.16   *Protein Phosphatase 2.
B56delta phosphatase, Xenopus  EC 3.1.3.16   *Xenopus Proteins *Protein Phosphatase 2. Cell 2006 Nov 17;127(4):759-73
Ppp2ca protein, rat  EC 3.1.3.16   *Protein Phosphatase 2. J Biol Chem 2004 Dec 3;279(49):51182-92
B56alpha protein, rat  EC 3.1.3.16   *Protein Phosphatase 2. Am J Physiol Heart Circ Physiol 2006 Sep;291(3):H1262-72
PPP2R2A protein, human  0   *Protein Phosphatase 2. Neoplasia 2006 May;8(5):413-8
PPP2R2B protein, human  EC 3.1.3.16   *Nerve Tissue Proteins *Protein Phosphatase 2 Spinocerebellar Ataxias. Ann Hum Genet 2005 Sep;69(Pt 5):528-34
PPP2R5C protein, human  EC 3.1.3.16   *Protein Phosphatase 2 Tumor Markers, Biological. Exp Hematol 2005 Aug;33(8):883-93
PPP2R5B protein, human  EC 3.1.3.16   *Membrane Proteins *Protein Phosphatase 2 Mitochondrial Proteins. J Biol Chem 2005 Jul 22;280(29):27375-82
ppp2r3a protein, Xenopus  EC 3.1.3.16   *Xenopus Proteins *Protein Phosphatase 2. Genes Dev 2005 Feb 1;19(3):376-86
PTC2 protein, S cerevisiae  EC 3.1.3.   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2.
SUR-6 protein, C elegans  EC 3.1.3.16   *Caenorhabditis elegans Proteins *Protein Phosphatase 2.
type 2A protein serine-threonine phosphatase 55 kDa B, Arabidopsis  EC 3.1.3.16.   *Arabidopsis Proteins *Protein Phosphatase 2.
Ppp2r5c protein, mouse  EC 3.1.3.16   *Protein Phosphatase 2. Cytogenet Genome Res 2003;103(3-4):345-51
PPH21 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2. Mol Biol Cell 2003 Nov;14(11):4342-51
RCN1 protein, Arabidopsis  EC 3.1.3.16   *Arabidopsis Proteins *Protein Phosphatase 2. Plant J 2003 Jun;34(5):709-18
Ppp2r5d protein, mouse  EC 3.1.3.16   *Protein Phosphatase 2. DNA Res. 2003 Apr 30;10(2):79-84
AtFyPP3 protein, Arabidopsis  EC 3.1.3.16   *Arabidopsis Proteins *Protein Phosphatase 2. Plant Cell 2002 Dec;14(12):3043-56
Pph22 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2. Eur J Biochem 2002 Jul;269(14):3372-82
PTC7 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2. IUBMB Life 2000 Dec;50(6):371-77
PPP2R1B protein, human  0   *Protein Phosphatase 2. Leuk Lymphoma 2001 Mar;41(1-2):177-83
PPP2R3B protein, human  0   *Protein Phosphatase 2. Mol Cel Biol 2000 Feb;20(3):1021-9
RGB-1protein, Neurospora crassa  EC 3.1.3.16   *Fungal Proteins *Protein Phosphatase 2. Mol Microbiol 1999 Jan;31(1):197-209
Ppp2r3a protein, mouse  EC 3.1.3.16   *Protein Phosphatase 2. Oncogene 1999 Jan 14;18(2):515-24
SIT4 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2.
PTC1 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2. Mol Cell Biol 1994 Jun;14(6):3634-45
Ppp2r1b protein, mouse  0   *Protein Phosphatase 2. Plant Mol Biol 1994 Feb;24(4):689-95
CDC55 protein, S cerevisiae  0   *Cell Cycle Proteins *Saccharomyces cerevisiae Proteins *Protein Phosphatase 2. Mol Cell Biol 1991;11(11):5767

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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