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Dual Specificity Phosphatase 2

More information in Books or onNLM PubMed
Definition: A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CELL NUCLEUS.      Other names Phosphatase, PAC1; Phosphatase, PAC-1; PAC 1 Phosphatase; PAC1 Phosphatase; PAC-1 Phosphatase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Dusp2 protein, rat  EC 3.1.3.48   *Dual Specificity Phosphatase 2.
Dusp2 protein, mouse  EC 3.1.3.48   *Dual Specificity Phosphatase 2.
DUSP2 protein, human  EC 3.1.3.48   *Dual Specificity Phosphatase 2.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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