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Protein Tyrosine Phosphatase, Non-Receptor Type 11

More information in Books or onNLM PubMed
Definition: A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME.      Other names Tyrosine Phosphatase, Shp-2; Shp 2 Tyrosine Phosphatase; SH Protein Tyrosine Phosphatase; Protein-Tyrosine Phosphatase, SH; Protein Tyrosine Phosphatase, Non Receptor Type 11; Protein Tyrosine Phosphatase 2C; Phosphatase, Shp-2 Tyrosine; Phosphatase, SHP2; Shp-2 Tyrosine Phosphatase; SHPTP2; SHP2 Phosphatase; SH Protein-Tyrosine Phosphatase; Protein-Tyrosine-Phosphatase 2C; Protein Tyrosine Phosphatase PTP3; Phosphotyrosine Phosphatase Syp
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HJ24 aptamer  0   *Aptamers, Nucleotide Protein Tyrosine Phosphatase, Non-Receptor Type 11/antagonists & inhibitors. Chembiochem 2011 Feb 11;12(3):424-30
3-(2-(5-(N-(4-fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid methyl ester  0   *Indoles *Sulfonamides Protein Tyrosine Phosphatase, Non-Receptor Type 11/antagonists & inhibitors. Biochem Pharmacol 2010 Sep 15;80(6):801-10
Ptpn11 protein, rat  EC 3.1.3.48   *Protein Tyrosine Phosphatase, Non-Receptor Type 11.
Ptpn11 protein, mouse  EC 3.1.3.48   *Protein Tyrosine Phosphatase, Non-Receptor Type 11.
PTPN11 protein, human  EC 3.1.3.48   *Protein Tyrosine Phosphatase, Non-Receptor Type 11.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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