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Group III Phospholipases A2

More information in Books or onNLM PubMed
Definition: A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.      Other names Phospholipase A2 III; Phospholipase A2-III; Group III Secretory Phospholipase A2; Phospholipases A2, Group III
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PLA2G3 protein, mouse  EC 3.1.1.4   *Group III Phospholipases A2. Biochem J 2009 Jul 1;421(1):17-27
PLA2G3 protein, human  EC 3.1.1.4   *Group III Phospholipases A2.
Pla2g3 protein, rat  EC 3.1.1.4   *Group III Phospholipases A2. Toxicon 1993 Aug;31(8):957-67

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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