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Agouti-Related Protein

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Definition: A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.      Other names Agouti Related Protein; AGRT Protein; AGRP Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Agrp protein, mouse  0   *Agouti-Related Protein.
AGRP protein, human  0   *Agouti-Related Protein.
AGRP protein, rat  0   *Agouti-Related Protein.
agouti-related protein (82-131), human  0   *Peptide Fragments *Agouti-Related Protein. Endocrinology 2005 Dec;146(12):5533-9
agouti-related protein (87-132), human  0   *Peptide Fragments *Agouti-Related Protein. J Med Chem 2004 Apr 22;47(9):2194-207
agouti-related protein (86-132), human  0   *Peptide Fragments *Agouti-Related Protein. Neurosci Lett 2001 Jun 8;305(2):131-4
agouti-related peptide, (Yc(CRFFNAFC)Y)  0   *Peptide Fragments *Agouti-Related Protein. Peptides 2000 May;21(5):683-9
agouti-related protein-(83-132)  0   *Peptide Fragments *Agouti-Related Protein. Am J Physiol Regul Integr Comp Physiol. 2000 Jul;279(1): R47-52

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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