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DNA Mismatch Repair

More information in Books or onNLM PubMed
Definition: A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)      Other names Repair, Mismatch; Repair, DNA Mismatch; Mismatch Repair, DNA; Mismatch Repair
 
SubstanceCAS Registry & nameCategoriesSource
Mlh1 protein, zebrafish  0   *Nuclear Proteins *Zebrafish Proteins *Adaptor Proteins, Signal Transducing DNA Mismatch Repair. Cell Tissue Res 2008 Apr;332(1):133-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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