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Transforming Growth Factor beta1

More information in Books or onNLM PubMed
Definition: A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.      Other names TGF beta1LAP; TGF beta1 Latency Associated Protein; TGF beta 1; Latency-Associated Protein, TGF-beta1; Transforming Growth Factor beta I; Transforming Growth Factor beta 1 Latency Associat; TGF-beta1LAP; TGF-beta1 Latency-Associated Protein; TGF-beta-1; TGF-beta1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(3,4-dimethoxyphenethyl)-N-methyl-3-(3-pyridyl)-2-propenamide  0   *Acrylamides *Pyridines Transforming Growth Factor beta1. Biol Pharm Bull 2010;33(8):1349-54
Tgfb1 protein, rat  0   *Transforming Growth Factor beta1.
Tgfb1 protein, mouse  0   *Transforming Growth Factor beta1.
TGFB1 protein, human  0   *Transforming Growth Factor beta1.
N-FLAG-TGF-beta1  0   *Transforming Growth Factor beta1 Recombinant Proteins. J Immunol Methods 2002 Aug 1;266(1-2):7-18
transforming growth factor beta1 (41-65)  0   *Peptide Fragments *Transforming Growth Factor beta1. FASEB J 2002 Aug;16(10):1269-70

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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