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Receptor, Interferon alpha-beta

More information in Books or onNLM PubMed
Definition: A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.      Other names Interferon alpha Receptor; IFN-alphabetaR; IFN-alphaR; alpha-beta Receptor-2, Interferon; alpha-beta Receptor-1, Interferon; alpha Receptors, Interferon; alpha Receptor, Interferon; Receptors, Interferon alphabeta; Receptors, Interferon alpha; Receptor-2, Interferon alpha-beta; Receptor-1, Interferon alpha-beta; Receptor, Interferon alpha beta; Interferon alpha beta Receptor IFNAR2 Subunit; Interferon alpha beta Receptor IFNAR1 Subunit; Interferon alpha beta Receptor Chain 2; Interferon alpha beta Receptor Chain 1; Interferon alpha beta Receptor 2; Interferon alpha beta Receptor 1; Interferon alpha beta Receptor; IFNAR2.2 Subunit, Interferon alpha beta Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ifnar2 protein, mouse  0   *Receptor, Interferon alpha-beta.
IFNAR2 protein, human  0   *Receptor, Interferon alpha-beta.
Ifnar1 protein, mouse  0   *Receptor, Interferon alpha-beta.
IFNAR1 protein, human  0   *Receptor, Interferon alpha-beta.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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