encyclopedia of medical concepts
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Interleukin 1 Receptor Antagonist Protein

More information in Books or onNLM PubMed
Definition: A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.     
Pharmacological Action Antirheumatic Agents 		Other names Urine IL-1 Inhibitor; Urine Derived IL1 Inhibitor; IL1 Inhibitor, Urine-Derived; IL 1 Inhibitor, Urine; Febrile Inhibitor, IL1; Anakinra Synergen Brand; Anakinra Amgen Brand; Urine-Derived IL1 Inhibitor; Synergen Brand of Anakinra; Kineret; Interleukin 1 Inhibitor, Urine; IL1 Febrile Inhibitor; IL-1Ra; IL-1 Inhibitor, Urine; Antril; Anakinra; Amgen Brand of AnakinraDrugs* : KINERET
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Deficiency of interleukin-1 receptor antagonist  0   *Hereditary Autoinflammatory Diseases Interleukin 1 Receptor Antagonist Protein.
Il1rn protein, mouse  0   *Interleukin 1 Receptor Antagonist Protein.
IL1RN protein, human  0   *Interleukin 1 Receptor Antagonist Protein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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