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Arsenate Reductases

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Definition: Oxidoreductases that specifically reduce arsenate ion to arsenite ion. Reduction of arsenate is a critical step for its biotransformation into a form that can be transported by ARSENITE TRANSPORTING ATPASES or complexed by specific sulfhydryl-containing proteins for the purpose of detoxification (METABOLIC DETOXIFICATION, DRUG). Arsenate reductases require reducing equivalents such as GLUTAREDOXIN or AZURIN.      Other names Reductases, Arsenate; Reductase, Arsenate; Arsenate Reductase-(Glutaredoxin); Arsenate Reductase (Glutaredoxin); Arsenate Reductase (Donor); Arsenate Reductase (Azurin); Arsenate Reductase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ARR2 protein, S cerevisiae  EC 1.20.-   *Saccharomyces cerevisiae Proteins *Arsenate Reductases.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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