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Caspase 10

More information in Books or onNLM PubMed
Definition: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.     
See Also Autoimmune Lymphoproliferative Syndrome 		Other names Protease, Mch4; Caspase 10 d; Caspase 10 c; Caspase 10 a; Mch4 Protease; Caspase-10; Caspase 10d; Caspase 10c; Caspase 10a; Caspase 10-d; Caspase 10-c; Caspase 10-a
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CASP10 protein, human  0   *Caspase 10.
interleukin 1beta-converting enzyme 2  EC 3.4.22.-   *Caspase 10 Apoptosis. J Biol Chem 1997 Mar 7;272(10):6578-83

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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