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Fanconi Anemia Complementation Group L Protein

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Definition: An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.      Other names Ubiquitin Ligase Protein PHF9; PHD Finger Protein 9; Fanconi Anemia Group L Protein; Fanconi Anemia Group L Complementing Protein; FANCL Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FANCL protein, human  EC 6.3.2.19   *Fanconi Anemia Complementation Group L Protein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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