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Fanconi Anemia Complementation Group D2 Protein

More information in Books or onNLM PubMed
Definition: A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.      Other names Fanconi Anemia Group D2 Protein; Fanconi Anemia Group D2 Complementing Protein; FANCD2 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Fancd2 protein, Drosophila  0   *Drosophila Proteins *Fanconi Anemia Complementation Group D2 Protein.
FANCD2 protein, human  0   *Fanconi Anemia Complementation Group D2 Protein.
Fancd2 protein, mouse  0   *Fanconi Anemia Complementation Group D2 Protein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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