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Phospholipase C gamma

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Definition: A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.      Other names PLC gamma 2; Phospholipase C gammaD; Phospholipase C gamma2; Phospholipase C gamma1; Phospholipase C gamma D; Phospholipase C gamma 2; Phospholipase C gamma 1; PLCgamma2; PLC-gamma D; PLC-gamma 2; PLC-gamma; PLC gamma1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PLCG1 protein, human  EC 3.1.4.11   *Phospholipase C gamma.
Plcg1 protein, mouse  EC 3.1.4.3   *Phospholipase C gamma. Mamm Genome 1999 Jan;10(1):62-7
SL protein, Drosophila  EC 3.1.4.3   *Drosophila Proteins *Phospholipase C gamma. Development 1998 Dec;125(24):5033-42

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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