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gamma-Synuclein

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Definition: A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpressed in a variety of human NEOPLASMS and may be involved in modulating AXON architecture during EMBRYONIC DEVELOPMENT and in the adult. Gamma-Synuclein may also activate SIGNAL TRANSDUCTION PATHWAYS associated with ETS-DOMAIN PROTEIN ELK-1.      Other names gamma Synuclein; Synoretin; Persyn
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SNCG protein, human  0   *Neoplasm Proteins *gamma-Synuclein Breast Neoplasms. Cancer Res 1997 Feb 15;57(4):759-64; Hum Mol Genet 1998 Sep;7(9):1417-1424

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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