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Actin Depolymerizing Factors

More information in Books or onNLM PubMed
Definition: A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.     
Examples Cofilin 1; Cofilin 2; Destrin 		Other names Depolymerizing Proteins, Actin; Depolymerizing Factors, Actin; Cofilin Proteins; Actin Depolymerizing Proteins; ADF Proteins (Actin Depolymerizing Factors); Cofilins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ADF4 protein, Arabidopsis  0   *Arabidopsis Proteins *Actin Depolymerizing Factors. Plant Physiol. 2009 Jun;150(2):815-24
Adf1 protein, S pombe  0   *Schizosaccharomyces pombe Proteins *Actin Depolymerizing Factors. Mol Biol Cell 2006 Apr;17(4):1933-45

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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