Definition: A heterotetrameric transcription factor composed of two distinct proteins. Its name refers to the fact it binds to DNA sequences rich in GUANINE and ADENINE. GA-binding protein integrates a variety of SIGNAL TRANSDUCTION PATHWAYS and regulates expression of GENES involved in CELL CYCLE control, PROTEIN BIOSYNTHESIS, and cellular METABOLISM.
Other names Transcription Factor, GABP; Respiratory Factor-2, Nuclear; GA Binding Protein, Beta Subunit; GA Binding Protein, Alpha Subunit; GA Binding Protein Transcription Factor; GA Binding Protein; Nuclear Respiratory Factor-2; Nuclear Respiratory Factor 2, Beta Subunit; Nuclear Respiratory Factor 2, Alpha Subunit; GABP Transcription Factor; GA-Binding Protein, Beta Subunit; GA-Binding Protein, Alpha Subunit; GA-Binding Protein; Nuclear Respiratory Factor 2
