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Wnt Proteins

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Definition: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.     
Examples Wnt1 Protein; Wnt2 Protein; Wnt3 Protein; Wnt3A Protein; Wnt4 Protein 		Other names Wnt Factors; Wingless Type Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
WNT2A protein, mouse  0   *Wnt Proteins. Development 2011 Aug;138(15):3169-77
wnt16 protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins. Nature. 2011;474(7350):220-4
Wnt9a protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins. Gene Expr Patterns 2010 Sep;10(6):251-8
Wnt5a protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins. Dev Biol 2009 Dec 1;336(1):68-75
CWN-2 protein, C elegans  0   *Caenorhabditis elegans Proteins *Wnt Proteins. Development 2009 Nov;136(22):3801-10
Wnt11 protein, human  0   *Wnt Proteins. Cell Stem Cell 2009 Mar 6;4(3):248-62
Wnt9b protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins. Zebrafish 2008 Sep;5(3):169-77
Wnt7b protein, rat  0   *Wnt Proteins. Differentiation 2008 Sep;76(7):795-808
Wnt6 protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins. Oncogene 1992 Oct;7(10):1941-7
CWN-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Wnt Proteins. Development 2007 Nov;134(22):4053-62
Wnt-9a protein, rat  0   *Wnt Proteins. Ann N Y Acad Sci 2007 Nov;1117:175-80
Wnt9b protein, mouse  0   *Wnt Proteins. Genomics 2003 Jan;81(1):34-46
wnt-11 protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins.
Wnt11 protein, mouse  0   *Wnt Proteins. BMC Cell Biol 2006;7() (dup#4):4
Wnt5b protein, rat  0   *Wnt Proteins. Int J Mol Med 2005 Apr;15(4):749-53
WNT9B protein, rat  0   *Wnt Proteins. Int J Mol Med 2005 Apr;15(4):743-7
Wnt11 protein, rat  0   *Wnt Proteins. Int J Mol Med. 2005 May;15(5):879-83
Wnt10b protein, rat  0   *Wnt Proteins Membrane Glycoproteins. Int J Oncol 2005 Mar;26(3):841-5
Wnt10a protein, rat  0   *Wnt Proteins. Int J Mol Med 2005 Mar;15(3):527-31
Wnt6 protein, rat  0   *Glycoproteins *Wnt Proteins. Int J Mol Med 2005 Mar;15(3):527-31
Wnt11-R protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins. Dev Biol 2005 Mar 1;279(1):179-92
wnt8a protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins.
wnt2b protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins.
Wnt2b protein, mouse  0   *Wnt Proteins Hematopoiesis.
Wnt2b protein, rat  0   *Wnt Proteins Hematopoiesis.
Wnt-5 protein, sea urchin  0   *Egg Proteins *Wnt Proteins.
Wnt5a protein, rat  0   *Wnt Proteins. FEBS Lett 2004 Aug 27;573(1-3):202-6
Wnt5 protein, Drosophila  0   *Proto-Oncogene Proteins *Drosophila Proteins *Wnt Proteins. Development 1992 Jun;115(2):475-85
wnt10b protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins.
WNT10B protein, human  0   *Proto-Oncogene Proteins *Wnt Proteins.
Xwnt7B protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins.
WNT7B protein, human  0   *Wnt Proteins.
WNT6 protein, human  0   *Wnt Proteins.
WNT8B protein, human  0   *Wnt Proteins Nerve Tissue Proteins.
Wnt8b protein, mouse  0   *Wnt Proteins Nerve Tissue Proteins.
Wnt8b protein, Xenopus  0   *Xenopus Proteins *Wnt Proteins Nerve Tissue Proteins.
WNT7A protein, Gallus gallus  0   *Avian Proteins *Wnt Proteins.
Wnt7a protein, mouse  0   *Wnt Proteins.
Wnt7a protein, rat  0   *Proto-Oncogene Proteins *Wnt Proteins.
Wnt9a protein, mouse  0   *Wnt Proteins.
Wnt10a protein, mouse  0   *Nerve Tissue Proteins *Wnt Proteins.
WNT10A protein, human  0   *Wnt Proteins.
Wnt5a protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins. Mech Dev 2003 Apr;120(4):467-76
Wnt5b protein, mouse  0   *Wnt Proteins. Nat Immunol 2002 Nov;3(11):1102-8
Wnt4 protein, Drosophila  0   *Glycoproteins *Drosophila Proteins *Wnt Proteins. Dev Cell 2002 Apr;2(4):437-48
WNT9B protein, human  0   *Wnt Proteins. Int J Oncol 2001 Nov;19(5);947-52
Wnt5a protein, mouse  0   *Wnt Proteins. Genomics 1994 Nov 1;24(1):9-13
WNT5B protein, human  0   *Wnt Proteins. Int J Oncol 2001 Aug;19(2):347-51
Wnt10 protein, Drosophila  0   *Drosophila Proteins *Wnt Proteins. Mech Dev 2001 May;103(1-2):117-20
Wnt6 protein, Drosophila  0   *Drosophila Proteins *Wnt Proteins. Mech Dev 2001 May;103(1-2):117-20
WNT16 protein, human  0   *Wnt Proteins. Proc Natl Acad Sci U S A 1999 Sep 28;96(20):11464-9
WNT2B protein, human  0   *Glycoproteins *Wnt Proteins Hematopoiesis. Blood 1998 Nov 1;92(9):3189-202; Oncogene 1996 Aug 15;13(4):873-6
Wnt-5 protein, Halocynthia roretzi  0   *Egg Proteins *Wnt Proteins. Int J Dev Biol 1998 May;42(4):573-9
WNT9A protein, human  0   *Wnt Proteins. Genomics 1997 Dec 15;46(3):450-8
Wnt-10a protein, Pleurodeles waltl  0   *Amphibian Proteins *Wnt Proteins. Dev Dyn 1997 Feb;208(2):139-48
Wnt10b protein, mouse  0   *Wnt Proteins. Genomics 1994 Nov 1;24(1):9-13; Oncogene 1996 Oct 3;13(7):1537-44
Wnt7b protein, mouse  0   *Proto-Oncogene Proteins *Wnt Proteins. Exp Cell Res 1995 Oct;220(2):363-73
Wnt6 protein, mouse  0   *Proto-Oncogene Proteins *Wnt Proteins. Exp Cell Res 1995 Oct;220(2):363-73
wnt8b protein, zebrafish  0   *Zebrafish Proteins *Wnt Proteins Nerve Tissue Proteins. Development 1995 Jun;121(6):1787-99
wnt8a protein, zebrafish  0   *Cytoskeletal Proteins *Zebrafish Proteins *Wnt Proteins. Development 1995 Jun;121(6):1787-99
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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