Definition: A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Other names p65 Protein (Synaptotagmin I); Synaptotagmin 1; Synaptic Vesicle Protein p65