encyclopedia of medical concepts
ψ
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Transcription Factor Brn-3C
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Definition
: A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha internexin, and SYNAPTOSOMAL-ASSOCIATED PROTEIN 25. Mutations in the Brn-3c gene have been associated with DEAFNESS.
Other names
Transcription Factor, Pou4f3; Transcription Factor, Brn-
3c; Transcription Factor Brn 3C; Brn-
3C, Transcription Factor; Brn 3c Transcription Factor; POU Domain, Class 4, Transcription Factor 3; Pou4f3 Transcription Factor; Brn-
3c Transcription Factor
Substance
CAS Registry & name
Categories
Source
Drugs
*
Pou4f3 protein, mouse
0
*Homeodomain Proteins
*Transcription Factor Brn-3C.
Hear Res 1999 Aug;134(1-2):71-6
POU4F3 protein, human
0
*Homeodomain Proteins
*Transcription Factor Brn-3C.
Science 1998 Mar 20;279(5358):1950-4