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E2F6 Transcription Factor

More information in Books or onNLM PubMed
Definition: An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.  see SCR for organism-specific terms    Other names Transcription Factor, E2F6; Transcription Factor E2F 6; E2F-6, Transcription Factor; Transcription Factor E2F-6; E2F Transcription Factor 6 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
E2f6 protein, rat  0   *E2F6 Transcription Factor.
E2F6 protein, human  0   *E2F6 Transcription Factor Repressor Proteins.
E2f6 protein, mouse  0   *E2F6 Transcription Factor Nuclear Proteins Repressor Proteins. Nature 1997 Dec 11;390(6660):567-8; Pro Natl Acad Sci U S A 1998 Mar 17;95(6):2850-5

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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