Vesicular Glutamate Transport Proteins (definition)

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Vesicular Glutamate Transport Proteins

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Definition: A family of vesicular neurotransmitter transporter proteins that were originally characterized as sodium dependent inorganic phosphate cotransporters. Vesicular glutamate transport proteins sequester the excitatory neurotransmitter GLUTAMATE from the CYTOPLASM into SECRETORY VESICLES in exchange for lumenal PROTONS.

Examples Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2

Other names Vesicular Glutamate Transporters; Transporters, Vesicular Glutamate; Transport Proteins, VGLUT; VGLUT Transport Proteins; Vesicular Glutamate Transporter Proteins; Glutamate Transporters, Vesicular

Substance	CAS Registry & name	Categories	Source	Drugs*
Vglut3 protein, rat	0	*Vesicular Glutamate Transport Proteins.	J Comp Neurol 2004 Jan 12;468(3):300-94
SLC17A8 protein, human	0	*Vesicular Glutamate Transport Proteins.	J Neurosci 2002 Jul 1;22(13):5442-51

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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