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TRPM Cation Channels

More information in Books or onNLM PubMed
Definition: A subgroup of TRP cation channels named after melastatin protein. They have the TRP domain but lack ANKYRIN repeats. Enzyme domains in the C-terminus leads to them being called chanzymes.      Other names Channels, TRPM Cation; Cation Channels, TRPM; Transient Receptor Potential Channels, Type M
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TRPM5 protein, rat  0   *TRPM Cation Channels. Circ Res. 2004 Oct 29;95(9):922-9.
waixenicin A  0   *Acetates *Diterpenes TRPM Cation Channels/antagonists & inhibitors. J Biol Chem. 2011 Nov 11;286(45):39328-35.
3-(7-trifluoromethyl-5-(2-trifluoromethylphenyl)-1H-benzimidazol-2-yl)-1-oxa-2-azaspiro(4.5)dec-2-ene  0   *Benzimidazoles *Isoxazoles TRPM Cation Channels/antagonists & inhibitors. J Med Chem 2011 Jan 13;54(1):233-47
Trpm2 protein, rat  0   *TRPM Cation Channels. J Mol Neurosci 2010 Oct;42(2):192-9
TRPM7 protein, Xenopus  0   *Xenopus Proteins *TRPM Cation Channels. Dev Biol 2011 Feb 15;350(2):348-57
GTL-2 protein, C elegans  0   *Caenorhabditis elegans Proteins *TRPM Cation Channels. PLoS One 2010;5(3):e9589
TRPM protein, Drosophila  0   *Drosophila Proteins *TRPM Cation Channels. PLoS One 2010;5(5):e10519
TRPM2 protein, mouse  0   *TRPM Cation Channels. Sci Signal. 2009;2(71):ra23
TRPM3 protein, mouse  0   *TRPM Cation Channels. Nat Cell Biol 2008 Dec;10(12):1421-30
TRPM3 protein, rat  0   *TRPM Cation Channels. Nat Cell Biol 2008 Dec;10(12):1421-30
Trpm6 protein, mouse  0   *TRPM Cation Channels. Am J Physiol Regul Integr Comp Physiol 2008 Jun;294(6):R2001-7
TRPM6 protein, rat  0   *TRPM Cation Channels. Am J Physiol Regul Integr Comp Physiol 2006 Jan;290(1):R73-8
Trpm7 protein, zebrafish  EC 2.7.1.37   *Zebrafish Proteins *TRPM Cation Channels Zebrafish Proteins. Curr Biol 2005 Apr 12;15(7):667-71
TRPM4 protein, rat  0   *TRPM Cation Channels. Circ Res 2004 Oct 29;95(9):922-9
Trpm8 protein, rat  0   *TRPM Cation Channels.
Trpm5 protein, mouse  0   *TRPM Cation Channels.
TRPM8 protein, mouse  0   *TRPM Cation Channels. Br J Pharmacol 2004 Feb;141(4);737-45
TRPM1 protein, human  0   *TRPM Cation Channels.
Trpm7 protein, rat  EC 2.7.11.1   *TRPM Cation Channels.
TRPM7 protein, human  EC 2.7.1.-   *TRPM Cation Channels Zinc Fingers.
TRPM4 protein, mouse  0   *TRPM Cation Channels. Biochem Biophys Res Commun 2003 Aug 1;307(3):522-8
TRPM3 protein, human  0   *TRPM Cation Channels. J Biol Chem 2003 Jun 13;278(24):21493-501
TRPM6 protein, human  0   *TRPM Cation Channels. Nat Genet 2002 Jun;31(2):166-70
TRPM4 protein, human  0   *TRPM Cation Channels. Proc Natl Acad Sci U S A 2001 Sep 11;98(19):10692-7
TRPM8 protein, human  0   *TRPM Cation Channels. Cancer Res 2001 May 1;61(9):3760-9
Trpm7 protein, mouse  EC 2.7.1.-   *TRPM Cation Channels Zinc Fingers. Science 2001 Feb 9;291(5506):1043-7
TRPM5 protein, human  0   *TRPM Cation Channels. Hum Mol Genet 2000 Jan 22;9(2):203-16
TRPM2 protein, human  0   *TRPM Cation Channels. J Biol Chem 1999 Sep 24;274(39):27359-70
Trpm1 protein, mouse  0   *TRPM Cation Channels. Genomics 1998 Nov 15;54(1):116-23

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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