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Sodium Chloride Symporters
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Definition
: A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS.
coordinate with DIURETICS if pertinent
See Also
Gitelman Syndrome
Other names
Transporter, Sodium-
Chloride; Symporters, Sodium Chloride; Sodium Chloride Transporter; Sodium Chloride Cotransporter; Na Cl Symporters; Cotransporters, Sodium Chloride; Cotransporter, Sodium-
Chloride; Chloride Symporters, Sodium; Chloride Cotransporters, Sodium; Sodium-
Chloride Transporter; Sodium-
Chloride Cotransporter; Sodium Chloride Cotransporters; Na-
Cl-
Symporters
Substance
CAS Registry & name
Categories
Source
Drugs
*
SLC12A10.2 protein, zebrafish
0
*Zebrafish Proteins
*Sodium Chloride Symporters.
Am J Physiol Regul Integr Comp Physiol 2009 May;296(5):R1650-60
thiazide receptor
0
*Receptors, Drug
*Sodium Chloride Symporters.
Clin Exp Hypertens (A) 1990;12(2):215; J Am Soc Nephrol. 2003 Feb;14(2):538-40