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MAP Kinase Kinase Kinase 5

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Definition: A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE 4; and MAP KINASE KINASE 6.      Other names MAPK Kinase Kinase 5; ASK1 Protein Kinase; Protein Kinase, MAP3K5; Protein Kinase, ASK1; Mitogen Activated Kinase Kinase Kinase Kinase 5; Apoptosis Signal Regulating Kinase 1; Mitogen-Activated Kinase Kinase Kinase Kinase 5; MAPKKK5; MAP3K5 Protein Kinase; Apoptosis Signal-Regulating Kinase 1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Map3k5 protein, mouse  EC 2.7.11.25   *MAP Kinase Kinase Kinase 5.
MAP3K5 protein, human  EC 2.7.11.25   *MAP Kinase Kinase Kinase 5.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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