Definition: A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.
Other names Stress Activated Protein Kinase Kinase 1; SAPK ERK Kinase 1; SAP Kinase Extracellular Signal Regulated Kinase K; Protein Kinase, SEK1; Protein Kinase, MEK4; Protein Kinase, JNKK1; Protein Kinase, JNK-Activating; Mitogen Activated Protein Kinase Kinase 4; Kinase, JNKK1 Protein; Jun Amino Terminal Kinase Kinase; JNK Activating Protein Kinase; Stress-Activated Protein Kinase Kinase 1; SEK1 Protein Kinase; SAPK-ERK Kinase 1; SAP Kinase-Extracellular Signal-Regulated Kinase K; SAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinase 4; MEK4 Protein Kinase; Jun Amino-Terminal Kinase Kinase; JNKK1 Protein Kinase
