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Peroxisome Proliferator-Activated Receptors

More information in Books or onNLM PubMed
Definition: TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and bind to peroxisome proliferator response elements in the promoter regions of target genes.  note specifics   
See Also Peroxisome Proliferators
Examples PPAR alpha; PPAR-beta; PPAR delta; PPAR gamma 		Other names Proliferator-Activated Receptors, Peroxisome; Peroxisome Proliferator Activated Receptors; PPAR, NUC1; NUC1 PPAR; PPAR; Receptors, Peroxisome Proliferator-Activated
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TIPP 703  0   *Phenylpropionates Adamantane/*analogs & derivatives Peroxisome Proliferator-Activated Receptors/agonists. Acta Crystallogr D Biol Crystallogr 2009 Aug;65(Pt 8):786-95
2-(5-(3-(6-benzoyl-1-propylnaphthalene-2-yloxy)propoxy)indol-1-yl)ethanoic acid  0   *Indoleacetic Acids *Naphthalenes Peroxisome Proliferator-Activated Receptors/agonists. J Med Chem 2006 Feb 9;49(3):1212-6
7-(3-(2-chloro-4-(2,2,2-trifluoroethoxy)phenoxy)propoxy)-3,4-dihydro-2-methyl-2H-benzopyran-2-carboxylic acid  0   *Benzopyrans Peroxisome Proliferator-Activated Receptors/agonists. Xenobiotica 2004 Jul;34(7):665-74
7-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)-2-ethyl-3,4-dihydro-2H-benzopyran-2-carboxylic acid  0   *Benzopyrans Peroxisome Proliferator-Activated Receptors/agonists. Xenobiotica 2004 Jul;34(7):665-74

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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