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Peroxisome Proliferator-Activated Receptors
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Definition
: TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and bind to peroxisome proliferator response elements in the promoter regions of target genes.
note specifics
See Also
Peroxisome Proliferators
Examples
PPAR alpha
;
PPAR-beta
;
PPAR delta
;
PPAR gamma
Other names
Proliferator-
Activated Receptors, Peroxisome; Peroxisome Proliferator Activated Receptors; PPAR, NUC1; NUC1 PPAR; PPAR; Receptors, Peroxisome Proliferator-
Activated
Substance
CAS Registry & name
Categories
Source
Drugs
*
TIPP 703
0
*Phenylpropionates
Adamantane/*analogs & derivatives
Peroxisome Proliferator-Activated Receptors/agonists.
Acta Crystallogr D Biol Crystallogr 2009 Aug;65(Pt 8):786-95
2-
(5-
(3-
(6-
benzoyl-
1-
propylnaphthalene-
2-
yloxy)propoxy)indol-
1-
yl)ethanoic acid
0
*Indoleacetic Acids
*Naphthalenes
Peroxisome Proliferator-Activated Receptors/agonists.
J Med Chem 2006 Feb 9;49(3):1212-6
7-
(3-
(2-
chloro-
4-
(2,2,2-
trifluoroethoxy)phenoxy)propoxy)-
3,4-
dihydro-
2-
methyl-
2H-
benzopyran-
2-
carboxylic acid
0
*Benzopyrans
Peroxisome Proliferator-Activated Receptors/agonists.
Xenobiotica 2004 Jul;34(7):665-74
7-
(3-
(2-
chloro-
4-
(4-
fluorophenoxy)phenoxy)propoxy)-
2-
ethyl-
3,4-
dihydro-
2H-
benzopyran-
2-
carboxylic acid
0
*Benzopyrans
Peroxisome Proliferator-Activated Receptors/agonists.
Xenobiotica 2004 Jul;34(7):665-74