encyclopedia of medical concepts
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Proprotein Convertase 2
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Definition
: A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.
Other names
PC2, Endopeptidase; Endoprotease, PC2; Convertase, PC2 Prohormone; Convertase PC2, Prohormone; Convertase PC2, Neuroendocrine; Convertase 2, Proinsulin; Convertase 2, Prohormone; Proinsulin Convertase 2; Prohormone Convertase PC2; Prohormone Convertase 2; PC2 Protein; PC2 Prohormone Convertase; PC2 Endoprotease; Neuroendocrine Convertase PC2; Endopeptidase PC2; Prohormone Convertase, PC2
Substance
CAS Registry & name
Categories
Source
Drugs
*
Pcsk2 protein, mouse
EC 3.4.21.94
*Proprotein Convertase 2.
Mol Endocrinol 1992 Sep;6(9):1441-50
EGL-
3 proprotein convertase, C elegans
EC 3.4.21.94
*Caenorhabditis elegans Proteins
*Proprotein Convertase 2.
J Neurosci 2001 Dec 1;21(23):9265-72