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Furin

More information in Books or onNLM PubMed
Definition: A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids.      Other names Processing Enzyme, Dibasic; SPC1 Proteinase; Paired Basic Amino Acid Cleaving Enzyme; Furin Protein; Dibasic Processing Enzyme
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-amino-4-acetylamino-3-(4-methylphenylamino)1H-pyrazole  0   *Pyrazoles Furin/antagonists & inhibitors. Ukr Biokhim Zh. 2011 Jan-Feb;83(1):30-7
hexaarginine amide  0   *Oligopeptides Furin/antagonists & inhibitors. Biochem Biophys Res Commun 2004 Aug 27;321(3):601-5
nonaarginine  0   *Oligopeptides Furin/antagonists & inhibitors. J Biol Chem 2004 Aug 27;279(35):36788-94
FURIN protein, human  EC 3.4.21.75   *Furin.
Fur1 protein, Drosophila  EC 3.4.21.75   *Furin *Drosophila Proteins. FEBS Lett 1991 Sep 9;289(2):133-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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