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Ubiquitin-Conjugating Enzymes
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Definition
: A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.
Other names
Ubiquitin Conjugating Enzymes; Ubiquitin Conjugating Enzyme E2; Enzymes, Ubiquitin-
Conjugating; Enzyme E2, Ubiquitin-
Conjugating; E2, Ubiquitin-
Conjugating Enzyme; Ubiquitin-
Conjugating Enzyme E2; HHR6 Protein
Substance
CAS Registry & name
Categories
Source
Drugs
*
Ubc12 protein, Drosophila
EC 6.3.2.19
*Drosophila Proteins
*Ubiquitin-Conjugating Enzymes.
PLoS One. 2011;6(9):e24168.
Atg3 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
FEBS J. 2006 Jun;273(11):2553-62.
UbcH10 protein, rat
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Cell Biochem Biophys 2011 Jun;60(1-2):89-97
Uev-
1 protein, C elegans
EC 6.3.2.19
*Caenorhabditis elegans Proteins
*Ubiquitin-Conjugating Enzymes.
PLoS One 2010;5(12):e14291
Ubc4 protein, S pombe
EC 6.3.2.19
*Schizosaccharomyces pombe Proteins
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 2011 Apr 15;286(15):13775-90
UBE2W protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Mol Cells 2011 Feb;31(2):113-22
Ubc5c protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Cell 2010 Apr 16;141(2):315-30
UbcH10 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Cell Biol 2010 Jan 11;188(1):83-100
UBE2J2 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Cell Biol. 2009 Nov 30;187(5):655-68
Ube2S protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Proc Natl Acad Sci U S A 2009 Oct 27;106(43):18213-8
Ubc7 protein, S pombe
EC 6.3.2.19
*Schizosaccharomyces pombe Proteins
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 2009 Jul 31;284(31):20512-21
GTAP protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Stem Cells 2008 Aug;26(8):2006-18
Hip-
2 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Cell Biol 2008 Aug 25;182(4):675-84
UEV1D protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Plant Cell 2008 Jan;20(1):213-27
UBE2Z protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Mol Biol Rep 2007 Sep;34(3):183-8
CROC1 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 2007 Oct 12;282(41):29936-45
E2-
EPF protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 1997 Nov 7;272(45):28198-201
UbcH8 protein, Drosophila
EC 6.3.2.19
*Drosophila Proteins
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 1999 Oct 22;274(43):30963-8
UBE2G2 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Nature. 2007 Mar 15;446(7133):333-7
Ubc13 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Biochim Biophys Acta 2001 May 28;1519(1-2):70-7
PHO2 protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Plant Physiol 2006 Jul;141(3):988-99
UBE2T protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Mol Cell 2006 Aug;23(4):589-96
Mms2 protein, S pombe
EC 6.3.2.19
*Schizosaccharomyces pombe Proteins
*Ubiquitin-Conjugating Enzymes.
DNA Repair (Amst) 2002 Nov 3;1(11):869-80
Ubc13 protein, S pombe
EC 6.3.2.19
*Schizosaccharomyces pombe Proteins
*Ubiquitin-Conjugating Enzymes.
Mol Biol Cell 2006 Jul;17(7):2976-85
UBC13B protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Plant Mol Biol 2006 May;61(1-2):241-53
UBC13A protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Plant Mol Biol 2006 May;61(1-2):241-53
Ube2a protein, mouse
0
*Ubiquitin-Conjugating Enzymes.
MMS2 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Hypertension 2006 Jul;48(1):141-8
UBE2W protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Front Biosci 2006;11:1500-7
UBC-
16 protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Front Biosci 2006;11:1500-7
UBE2Q2 protein, human
EC 6.3.2.19
*Cytoskeletal Proteins
*Ubiquitin-Conjugating Enzymes
Hypopharyngeal Neoplasms.
Biochem Biophys Res Commun 2006 Jan 6;339(1):422-9
bruce protein, rat
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Cell Biol 1998 Jun 15;141(6):1415-22
Ube2b protein, rat
EC 6.3.2.-
*Ubiquitin-Conjugating Enzymes.
Mol Cell Neurosci 2005 Aug;29(4):559-68
UFC1 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
EMBO J 2004 May 5;23(9):1977-86
Ubc4 protein, S cerevisiae
EC 6.3.2.19
*Saccharomyces cerevisiae Proteins
*Ubiquitin-Conjugating Enzymes.
J Biol Chem 2005 Apr 8;280(14):13401-5
KUA protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
vihar protein, Drosophila
EC 6.3.2.19
*Drosophila Proteins
*Ubiquitin-Conjugating Enzymes.
Curr Biol 2004 Oct 5;14(19):1723-33
UbcM2 protein, mouse
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
J Cell Biol 2004 Nov 22;167(4):649-59
Ube2d1 protein, mouse
EC 6.3.2.19
*Iron-Binding Proteins
*Ubiquitin-Conjugating Enzymes.
UBE2J1 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
UBE2J2 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
UBE2E1 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
ubc-
1 protein, C elegans
EC 6.3.2.19
*Caenorhabditis elegans Proteins
*Ubiquitin-Conjugating Enzymes.
UBC1 protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
UbcD6 protein, Drosophila
0
*Drosophila Proteins
*Ubiquitin-Conjugating Enzymes.
UBC5 protein, S cerevisiae
EC 6.3.2.19
*Saccharomyces cerevisiae Proteins
*Ubiquitin-Conjugating Enzymes.
UBC20 protein, Arabidopsis
EC 6.3.2.19
*Arabidopsis Proteins
*Ubiquitin-Conjugating Enzymes.
Plant Physiol 2002 Nov;130(3):1230-40
UBE2V1 protein, human
EC 6.3.2.19
*Transcription Factors
*Ubiquitin-Conjugating Enzymes.
Oncogene 1998 Sep 10;17(10):1321-6
UBE2L6 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
UBE2L4 protein, human
0
*Ubiquitin-Conjugating Enzymes.
UBE2G2 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
UBE2G1 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
Ube2i protein, rat
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
effete protein, Drosophila
EC 6.3.2.19
*Drosophila Proteins
*Ubiquitin-Conjugating Enzymes.
UBC13 protein, S cerevisiae
EC 6.3.2.19
*Saccharomyces cerevisiae Proteins
*Ubiquitin-Conjugating Enzymes.
UBE2N protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
RAD6 protein, S cerevisiae
EC 6.3.2.19
*Saccharomyces cerevisiae Proteins
*Ubiquitin-Conjugating Enzymes.
UBE2L1 protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
UBE2B protein, human
0
*Ubiquitin-Conjugating Enzymes.
UBE2A protein, human
EC 6.3.2.19
*Ubiquitin-Conjugating Enzymes.
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